该资料来自非杂志,可信度一般,可参考。没有看全文。
这个水据说是来自日本日田的天然还原水,文章中没有说是含氢气水,但看该公司有这种说法,不知道具体细节。如果说这种水治疗糖尿病是因为含有丰富的氢气,那是有一定道理的。到目前已经有两篇关于氢气治疗人类糖尿病有效的论文了,尽管都属于初步临床观察,但仍有一定的可信度,也有关于电解含氢气水对糖尿病肾脏损伤的治疗作用报道。我们现在的研究和我了解的日本学者的研究都表明,氢气对动物糖尿病和脂肪肝以及糖尿病引起的并发症都有很理想的治疗效果(未发表)。但不知道这种水是否含有氢气,含有氢气的浓度是多少。患者需要每天多少水才能有这样的作用?这些问题需要明确。无论如何,希望这个报道是真实的,能找到无副作用,简单实用的治疗药物总是我们梦寐以求的。
日田市是天領時代的古城市,日田市是位于日本大分县西北部的一个城市,虽然隶属大分县,但因为地形的关系,与福冈县的筑前地方和筑后地方往来较为频繁。日田的水非常的有名!这个研究是不仅采用小鼠,而且观察了糖尿病患者,主要观察指标是蛋白酪氨酸磷酸酶(Protein tyrosine phosphatase ,PTP),PTP是一种氧化还原调节蛋白,该酶的激活与胰岛素受体抵抗关系密切。日本日田天領水具有抑制PTP活性,从而使胰岛素受体敏感的作用,在动物实验中观察到具有促进肌肉摄取葡萄糖的能力,在临床观察中发现饮用该水具有控制血糖和血脂的作用。
Kazuhiro Osada, Yuping Li, Takeki Hamasaki, Masumi Abe, Noboru Nakamichi, Kiichiro Teruya, Yoshitoki Ishii, Ying Wang, Yoshinori Katakura and Sanetaka Shirahata
Abstract
It has been reported that a natural reduced water derived from a deep well in Japan (trademark, Hita Tenryousui water®; Nakanoshima, Hita city, Oita, Japan) scavenged intracellular reactive oxygen species (ROS) and protected a hamster pancreas β cell line HIT-T15 from oxidative damage by alloxan, a type 1 diabetes inducer. Here we demonstrated that the water also suppressed the fasted blood glucose levels of the alloxan-induced type 1-diabetes mice. Protein tyrosine phosphatase (PTP) is a redox-regulatable signal enzyme and activation of PTP in Type 2-diabetes patients is noted to be responsible to inactivation of insulin receptor. Hita Tenryousui water® suppressed the PTP activity, leading the activation of insulin receptor. This water stimulated glucose uptake into myotubes and showed a tendency to improve the impaired sugar tolerance of Type 2-diabetes model mice. An open clinical test of Hita Tenryousui water® against 65 patients with hyperglycemia and 50 patients with hyperlipemia for 2 months resulted in significant improvement of impaired blood sugar, plasma triglycerol and total cholesterol levels (P<0.05). These facts suggest that daily intake of natural reduced water will be beneficial to prevent and improve diabetes mellitus.
Keywords Diabetes - Hita tenryosui water - Natural reduced water - Reactive oxygen species - Protein tyrosine phosphatase