王小凡，著名癌症生物学家。1955年出生于中国乌鲁木齐，1982年毕业于武汉大学生物化学专业，同年考入中国科学院遗传研究所，并在当年举办的首届"中美生物化学联合招生项目"(CUSBEA)中取得第一名的成绩赴美留学。1986年获加州大学洛杉矶分校博士学位，之后在麻省理工学院师从癌症生物学大家Robert A. Weinberg从事博士后研究。1992年被聘为杜克大学药理学和肿瘤生物学系助理教授，成为最早在杜克大学执教的华人教授之一。1998年成为终身教授，2003年晋升为正教授。现任杜克大学医学中心药理学和肿瘤生物学Donald and Elizabeth Cooke终身讲席教授。
https://baike.so.com/doc/6032825-6245827.html
祝贺科学网博主王小凡当选中国科学院外籍院士 精选
http://blog.sciencenet.cn/blog-45-1087214.html
王小凡院士科学网博客 http://blog.sciencenet.cn/u/wangxiaofan
美国PUBMED数据库检索到王小凡教授的学术论文77篇分布如下：
过敏性反应 1 1.299 王小凡教授的研究主题
01. carcinoma, pancreatic ductal 1 0.919405 02. tumor microenvironment 5 0.818678 03. interferon type i 1 0.685146 04. cyclin-dependent kinase inhibitor p21 5 0.365721 06. ataxia telangiectasia mutated proteins 1 0.261971 07. lymphangiogenesis 1 0.259754 09. endosomal sorting complexes required for transport 1 0.236948 12. genes, myc 1 0.136643 13. phosphorylation 13 0.101635 14. protein binding 4 0.101437 15. activin receptors, type i 1 0.0988361 16. cytokine receptor gp130 1 0.0905934 17. replication protein a 2 0.0868677 18. interphase 1 0.0819774 19. osteonectin 2 0.0535362 20. caspase 7 1 0.0506085 21. e2f transcription factors 1 0.0456275 22. mi-2 nucleosome remodeling and deacetylase complex 1 0.042829 23. tumor cells, cultured 5 0.0378357 24. mice, inbred balb c 3 0.0200761 25. hek293 cells 1 0.0150571 26. chemokine ccl22 1 0.0129061 27. methylation 1 0.0129061 28. casein kinases 1 0.010038 29. alkylation 1 0.00983829 30. e2f4 transcription factor 1 0.00803044 31. molecular sequence data 2 0.00501902 32. hct116 cells 1 0.00491914 34. antineoplastic agents 1 9.53895 35. breast neoplasms 6 9.53444 36. signal transduction 22 8.43001 37. lung neoplasms 4 7.75976 40. gene expression regulation 3 5.0048 41. liver neoplasms 3 4.67605 43. colorectal neoplasms 1 4.59909 44. transcription factors 5 4.55078 46. membrane proteins 1 3.65978 47. inflammation 2 3.40707 48. myocardial infarction 2 3.40408 49. carcinoma, squamous cell 1 3.38806 50. cell differentiation 4 3.33377 52. carcinoma, non-small-cell lung 1 3.10157 53. carcinoma, hepatocellular 2 2.99063 54. dna-binding proteins 14 2.91616 55. ovarian neoplasms 2 2.86523 56. gene expression regulation, neoplastic 9 2.8425 57. pancreatic neoplasms 3 2.84225 58. brain neoplasms 4 2.82246 59. macrophages 2 2.68843 60. nuclear proteins 4 2.67189 62. cell proliferation 12 2.66113 64. dna methylation 1 2.20325 65. cell movement 6 2.19387 66. carrier proteins 2 2.09281 68. drug resistance, neoplasm 2 1.96326 69. immunosuppressive agents 1 1.94145 70. epithelial cells 1 1.90782 71. cell membrane 1 1.82848 72. nerve tissue proteins 2 1.68639 74. endothelial cells 3 1.67188 75. rna, messenger 7 1.62348 76. neoplasm proteins 2 1.61418 77. adaptor proteins, signal transducing 3 1.54928 78. repressor proteins 2 1.53235 79. mesenchymal stromal cells 1 1.49023 80. tumor suppressor protein p53 2 1.47619 82. colonic neoplasms 1 1.46028 83. enzyme inhibitors 2 1.43774 84. transcription, genetic 4 1.42633 85. promoter regions, genetic 5 1.40286 86. homeodomain proteins 1 1.3788 87. gene expression profiling 3 1.37089 88. protein-serine-threonine kinases 11 1.34318 90. neovascularization, pathologic 4 1.32327 92. receptor, epidermal growth factor 2 1.24871 93. neoplastic stem cells 3 1.20518 94. tumor suppressor proteins 5 1.20212 95. fibroblasts 6 1.19501 96. intracellular signaling peptides and proteins 1 1.18154 97. proto-oncogene proteins c-akt 4 1.15855 98. glioblastoma 2 1.1491 100. endothelium, vascular 1 1.06848 102. cell nucleus 3 1.04496 103. fluorodeoxyglucose f18 1 1.02177 104. cell transformation, neoplastic 4 0.987719 105. benzamides 2 0.92314 106. dna repair 4 0.903851 107. interleukin-6 1 0.898911 108. cell cycle proteins 9 0.890146 109. recombinant fusion proteins 3 0.868004 110. map kinase signaling system 2 0.852396 112. protein processing, post-translational 3 0.837561 113. intercellular signaling peptides and proteins 1 0.815446 114. transforming growth factor beta 18 0.784269 115. membrane glycoproteins 1 0.781966 116. protein kinases 6 0.767788 117. trans-activators 9 0.749436 118. recombinant proteins 2 0.745389 119. phosphatidylinositol 3-kinases 4 0.734102 120. up-regulation 4 0.731336 121. down-regulation 1 0.702262 122. gene expression regulation, enzymologic 2 0.698357 123. rna, small interfering 8 0.694552 124. transcriptional activation 3 0.685567 125. antigens, cd 4 0.676159 126. beta catenin 1 0.657052 127. neoplasm metastasis 2 0.654942 128. cell adhesion molecules 1 0.645761 129. glycoproteins 2 0.645705 130. extracellular matrix 1 0.641636 131. keratinocytes 2 0.636326 132. ultraviolet rays 2 0.633654 133. endocytosis 1 0.611247 134. protein-tyrosine kinases 2 0.605647 135. antimetabolites, antineoplastic 1 0.601865 136. quinazolines 2 0.598265 138. apoptosis regulatory proteins 1 0.54923 139. hepatitis b virus 1 0.544576 140. cell lineage 1 0.511017 141. dna replication 4 0.501102 142. bone marrow cells 1 0.489952 143. disease progression 1 0.488287 144. chromosome aberrations 1 0.486625 145. hepatitis b 1 0.477023 146. transforming growth factor beta1 5 0.472551 147. wnt proteins 2 0.470714 149. rna interference 5 0.460499 150. microfilament proteins 1 0.454849 151. dna breaks, double-stranded 2 0.451323 153. matrix metalloproteinase 9 2 0.425792 154. neoplasm invasiveness 3 0.419478 155. cell survival 5 0.413224 156. graft survival 1 0.406669 157. cell cycle 6 0.404868 158. cell aging 2 0.39796 159. chromosomal proteins, non-histone 1 0.368043 160. cell adhesion 1 0.367936 161. heart transplantation 1 0.364931 162. fluorouracil 1 0.347956 164. chemokine cxcl12 1 0.341807 165. chemokines 1 0.340425 166. extracellular matrix proteins 2 0.340069 167. histone deacetylase inhibitors 1 0.333148 169. cell division 2 0.313513 170. flow cytometry 3 0.310542 171. oligonucleotide array sequence analysis 2 0.310425 172. glycogen synthase kinase 3 1 0.306586 173. cell death 1 0.301978 174. methyltransferases 1 0.296035 175. blood proteins 1 0.285527 176. cytoplasm 3 0.281094 177. fibronectins 1 0.275248 178. amyloid precursor protein secretases 1 0.274071 179. cell separation 2 0.272982 180. integrins 1 0.268425 181. bone morphogenetic proteins 2 0.266636 182. histone deacetylases 3 0.264394 183. cell hypoxia 1 0.263343 184. matrix metalloproteinase 2 1 0.258589 185. tumor burden 2 0.233127 186. mitogen-activated protein kinase 1 2 0.233127 187. chemokine ccl2 1 0.219873 189. phosphoprotein phosphatases 4 0.214575 190. macrophage activation 1 0.207453 191. dna repair enzymes 1 0.203422 192. gene dosage 1 0.196261 193. reverse transcriptase polymerase chain reaction 3 0.194234 194. cell cycle checkpoints 1 0.190114 195. gamma rays 1 0.187038 196. interleukin-18 1 0.18591 197. protein isoforms 2 0.185506 198. mitogen-activated protein kinase 3 2 0.174712 199. transfection 7 0.172235 200. caspase 3 1 0.166892 201. lymphocytes, tumor-infiltrating 1 0.164502 202. smad3 protein 12 0.160974 204. chemotaxis 1 0.158495 205. protein phosphatase 2 2 0.156341 206. feedback, physiological 1 0.151487 207. cyclin d1 1 0.144248 208. epidermal growth factor 1 0.142912 209. gene amplification 1 0.140666 210. cpg islands 1 0.138901 211. mammary glands, human 1 0.131207 212. dna mismatch repair 1 0.130806 213. centrosome 1 0.128301 214. receptors, transforming growth factor beta 6 0.123168 215. dna primers 1 0.120758 216. bronchoalveolar lavage fluid 1 0.118969 217. cyclic amp response element-binding protein 1 0.110054 218. focal adhesion kinase 1 1 0.107614 219. chromosomal instability 3 0.101772 220. integrin alphavbeta3 1 0.100774 221. focal adhesion protein-tyrosine kinases 1 0.100288 222. bleomycin 1 0.0970844 223. xenograft model antitumor assays 2 0.091872 224. 14-3-3 proteins 1 0.0904162 225. mesangial cells 1 0.0894298 226. base sequence 3 0.0892407 227. intercellular junctions 1 0.0889525 228. macrophage migration-inhibitory factors 1 0.0888734 229. autocrine communication 1 0.0881655 231. hyperplasia 1 0.0871159 232. ccaat-enhancer-binding proteins 1 0.0859422 233. smad2 protein 3 0.0856472 234. cdc2 protein kinase 1 0.0816942 235. enzyme activation 4 0.078134 236. binding sites 2 0.0769583 237. g2 phase 2 0.0754945 238. core binding factor alpha 1 subunit 1 0.0750898 239. genes, reporter 1 0.0748728 240. dioxoles 2 0.0746708 241. activins 1 0.0727414 242. interleukin-1 receptor-associated kinases 1 0.0707027 243. active transport, cell nucleus 1 0.0705111 244. matrix metalloproteinase 1 1 0.0680806 245. cell line, tumor 13 0.061483 246. matrix metalloproteinase 3 1 0.0610359 247. antigens, differentiation 1 0.0607302 248. mutagenesis 3 0.0601109 249. luciferases 1 0.0596074 251. diastole 1 0.0575061 253. hydroxyurea 2 0.0526997 254. karyotyping 1 0.0508946 255. cyclin-dependent kinase 2 1 0.0464618 256. immunoenzyme techniques 1 0.0452967 257. cyclophilin a 1 0.0427708 258. immunoprecipitation 2 0.0401522 259. transplantation, heterologous 4 0.0393649 260. g1 phase 2 0.0367106 261. smad proteins 3 0.036502 262. blotting, western 2 0.0358502 263. cell line 15 0.0347471 264. growth inhibitors 1 0.0347471 266. cdc25 phosphatases 1 0.033739 267. neoplasm transplantation 2 0.0325233 268. amino acid motifs 1 0.0317252 269. keratins 1 0.0309721 270. gastrointestinal hormones 1 0.0282738 271. mice, knockout 10 0.0279319 272. arteriosclerosis 1 0.0267681 273. axin protein 1 0.0188951 274. cyclin a 1 0.0164259 275. intermediate filaments 1 0.0152961 276. electrophoresis, polyacrylamide gel 1 0.0139417 277. cells, cultured 6 0.0125476 278. cell growth processes 2 0.0123545 279. time factors 4 0.0122966 280. cyclin b 1 0.0119501 281. ccaat-enhancer-binding protein-delta 1 0.0119501 282. activating transcription factors 1 0.00903424 283. hela cells 5 0.00764803 284. base pair mismatch 1 0.00697086 285. mice, inbred c57bl 4 0.00594847 286. holoenzymes 1 0.00573603 287. gene products, tax 1 0.00553823 288. amino acid sequence 2 0.00512145 289. culture media, serum-free 1 0.00486693 290. 3t3 cells 1 0.00334601 291. mice, nude 8 0.00327943 292. mice, scid 4 0.00327943 293. gene products, vpr 1 0.00163971 294. cdc2-cdc28 kinases 1 0.00111534 295. acetylation 1 0.000819857 296. dose-response relationship, radiation 1 0.000590473
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