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长期寻找的“温敏性”脑细胞在新研究中得到鉴定
Health
Long-sought 'warm-sensitive' brain cells identified in new study
A new UC San Francisco study challenges the most influential textbook explanation of how the mammalian brain detects when the body is becoming too warm, and how it then orchestrates the myriad responses that animals, including humans, use to lower their temperature-from "automatic" physiological processes such as sweating and panting, to complex behaviors, such as moving to cooler environs. These responses are vital to health, as the metabolic processes that keep us alive have evolved to operate within a narrow temperature range. Experiments on these questions dating back 80 years, using rats and mice, have repeatedly pointed to a tiny brain region known as the preoptic hypothalamus (POA) as
Medicalxpress.Com
突触连接基序有助于海马的记忆存储和检索
Science
Synaptic connectivity motifs contribute to memory storage and retrieval in hippocampus
The hippocampal CA3 region plays a key role in learning and memory. One of the most remarkable properties of the network is its ability to retrieve previously stored memories from incomplete or degraded versions, a phenomenon that is widely known as pattern completion. It is generally accepted that the synapses between CA3 pyramidal cells, the recurrent CA3-CA3 synapses, play a key role in pattern completion, but how this exactly works has remained enigmatic. In a recent research article entitled "Synaptic mechanisms of pattern completion in the hippocampal CA3 network", published on September 9, 2016, in Science, Jose Guzman, Alois Schlögl, Michael Frotscher, and Peter Jonas have investigated
Medicalxpress.Com
关闭这一新发现的大脑路径可以帮助我们阻止可怕的记忆
Science
Turning off this newly discovered brain pathway could help us block fearful memories
Scientists now know how to make you forget your fears - at least if you’re a mouse. By turning off a newly discovered brain pathway, scientists were able to make mice lose their fear of a shock. It’s early research, but it may point toward methods that could help people with anxiety and PTSD. After finding a new pathway in the brain important for creating fearful memories, scientists trained mice to fear a high-pitched tone by shocking the rodents every time they heard it, according to a study published today in Nature Neuroscience. They waited til the rodents would freeze in fear even without the shock before proceeding to the next stage: viewing the mouse brains. Using a specialized microscopy
The Verge
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