Local Auxin Biosynthesis Is a Key Regulator of Plant Development

First author: Javier Brumos; Affiliations: North Carolina State University (北卡罗来纳州立大学): Raleigh, USA

Corresponding author: Anna N. Stepanova

Auxin is a major phytohormone that controls numerous aspects of plant development and coordinates plant responses to the environment. Morphogenic gradients (形态发生梯度) of auxin govern cell fate decisions and underlie plant phenotypic plasticity. Polar auxin transport plays a central role in auxin maxima generation. The discovery of the exquisite (精致的) spatiotemporal (时空的) expression patterns of auxin biosynthesis genes of the WEI8/TAR and YUC families suggested that local auxin production may contribute to the formation of auxin maxima. Herein, we systematically addressed the role of local auxin biosynthesis in plant development and responses to the stress phytohormone ethylene by manipulating spatiotemporal patterns of WEI8. Our study revealed that local auxin biosynthesis and transport act synergistically (协同地) and are individually dispensable (不必要) for root meristem maintenance. In contrast, flower fertility and root responses to ethylene require local auxin production that cannot be fully compensated for by transport in the generation of morphogenic auxin maxima.

生长素是控制植物发育和协调植物响应外部环境的主要植物激素。生长素的形态发生梯度赋予了细胞命运决定，并作用于植物表型可塑性。极性生长素运输在生长素极大值点的形成中扮演重要作用。生长素生物合成基因WEI8/TAR和YUC基因家族的时空表达模式显示区域性的生长素合成可能作用于生长素极大值点的形成。本文，作者通过改变WEI8基因的时空表达模式研究了区域性生长素合成在植物发育和对乙烯胁迫响应中的作用。本文的研究揭示了区域性生长素生物合成和转运协同作用，并且合成或转运单个因素对于根分生组织的维持不是必要的。相反，花育性和根对于乙烯的响应需要区域性的生长素合成，并且不能被形态学上生长素极大值形成点的转运所完全补偿。

通讯：Anna N. Stepanova  (https://harvest.cals.ncsu.edu/applications/global_programs/faculty_overview_wp.cfm?ID=5750)

研究方向：利用拟南芥作为模式植物研究植物表型可塑性背后潜在的分子调控机制。

doi: https://doi.org/10.1016/j.devcel.2018.09.022

Journal: Developmental Cell

First Published: 25 October, 2018

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