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为什么癌症研究者论​文多次修改最终还是撤稿?

已有 4886 次阅读 2014-8-28 23:26 |个人分类:新观察|系统分类:海外观察| 撤稿, 分子内分泌, Rakesh, Kumar

 为什么癌症研究者论文多次修改最终还是为撤稿?

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据《撤稿瞭望》(Retraction Watch)网站2014828报道,美国乔治华盛顿大学医学与健康科学学院(SMHS)的研究者,Catharine Birch McCormick生化与分子生物学部主席、生物化学及分子生物学教授拉凯什·库马尔(Rakesh Kumar)博士等人在20078月发表于《分子内分泌学》(Molecular Endocrinology)的论文——Gururajet al, “Estrogen Induces Expression of BCAS3, A Novel Estrogen Receptor-alphaCoactivator, through Proline-, Glutamic Acid-, and Leucine-Rich Protein-1(PELP1)” (Mol Endocrinol 21:1847–1860, doi: 10.1210/me.2006-0514,尽管经过了6次修改,但是最终还是以撤稿而结束。本文最初发表的时候,拉凯什·库马尔是在美国乔治华盛顿大学从事生物化学研究,但是目前已经离开了乔治华盛顿大学。他是一位印度喀拉拉邦(Kerala)拉吉夫·甘地生物技术中心(Rajiv Gandhi Center for Biotechnology in Kerala, lndia)生物技术的特聘来访教授(visiting distinguished professor of biotechnology)。对于为何撤稿的原因目前尚未作出回应。根据汤姆森科技的知网(Thomson Scientific’s Web of Knowledge)统计结果,原论文已经被引用了九次。《撤稿瞭望》的相关信息摘引如下:

Retraction Watch

Tracking retractions as a window into the scientific process

Cancer researcher has correction upgraded to retraction

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Rakesh Kumar, a researcher with six recent corrections and one retraction, has had one of those corrections upgraded to a retraction.

Here’s the unhelpful notice, from Molecular Endocrinology:

The August 2007 Molecular Endocrinology article by by Gururaj et al, “Estrogen Induces Expression of BCAS3, A Novel Estrogen Receptor-alpha Coactivator, through Proline-, Glutamic Acid-, and Leucine-Rich Protein-1 (PELP1)” (Mol Endocrinol 21:1847–1860, doi: 10.1210/me.2006-0514), is withdrawn by the authors.

This was the correction:

In the August 2007 Molecular Endocrinology article by Gururaj et al. “Estrogen induces expression of BCAS3, a novel estrogen receptor-alpha coactivator, through proline-, glutamic acid-, and leucine-rich protein-1 (PELP1)” (Mol Endocrinol 21:1847–60; Epub 2007 May 15. PubMed PMID: 17505058; doi: 10.1210/me.2006–0514), the authors note certain inadvertent errors in the Actin mRNA lanes in Figure 3H and splicing in the pS2 ChIP in Figure 7A upper panel while composing the panels.


The authors are replacing the published Figures 3H and 7A panels with an erratum using data from repeat experiments. There is no change in the text and figure legends. These changes do not change the original scientific conclusions and the validity of the findings remains the same. The authors regret the error.

The original paper has been cited nine times, according to Thomson Scientific’s Web of Knowledge.

Kumar, who was at MD Anderson when the paper was originally published. appears to have left the George Washington University, where he was recently chair of biochemistry. He is a visiting distinguished professor of biotechnology at the Rajiv Gandhi Center for Biotechnology in Kerala, lndia. Our requests for comment from him have gone unanswered.






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