oxfordjournals.org[PDF]… , GY Li, Y Yu, B Liu, J Tangrea, Y Sun, … - … National Cancer …, 1993 - jnci.oxfordjournals.org Background: Epidemiologic evidence indicates that diets high in fruits and vegetables are associated with a reduced risk of several cancers, including cancers of the esophagus and stomach. Vitamins and minerals in these foods may contribute to the reduced cancer risk. The people of ... Cited by 1133 - Related articles - BL Direct - All 11 versions
ascopubs.org[PDF]H Mouridsen, M Gershanovich, Y Sun, R … - Journal of Clinical …, 2001 - jco.ascopubs.org Purpose: To compare the efficacy and tolerability of tamoxifen with that of letrozole, an oral aromatase inhibitor, with tamoxifen as first-line therapy in post- menopausal women with advanced breast cancer. Patients and Methods: Nine hundred seven patients were randomly assigned ... Cited by 746 - Related articles - BL Direct - All 11 versions
FO Nestle, S Alijagic, M Gilliet, Y Sun, S Grabbe, R … - Nature Medicine, 1998 - nature.com ... Objective responses were evident in 5 out of 16 evaluated patients (two complete responses, three partial responses) with regression of metastases in various organs (skin, soft tissue, lung, pancreas) and one ... | PubMed | ISI | ChemPort |; Rosenberg, SA Cancer vaccines based ... Cited by 2325 - Related articles - BL Direct - All 4 versions
aacrjournals.org[HTML]MZ Fang, Y Wang, N Ai, Z Hou, Y Sun, H Lu, W Welsh, … - Cancer research, 2003 - AACR Hypermethylation of CpG islands in the promoter regions is an important mechanism to silence the expression of many important genes in cancer. The hypermethylation status is passed to the daughter cells through the methylation of the newly synthesized DNA strand by 5- ... Cited by 300 - Related articles - BL Direct - All 8 versions
ascopubs.org[HTML]H Mouridsen, M Gershanovich, Y Sun, R … - Journal of Clinical …, 2003 - jco.ascopubs.org From the Rigshospitalet, Copenhagen, Denmark; Petrov Research Institute of Oncology, St Petersburg, Russia; Chinese Academy of Medical Sciences, Beijing, China; Hospital Universitario de la Princesa, Madrid, Spain; Arcipedale Santa Maria Nuova, Reggio Emilia, Italy; ... Cited by 405 - Related articles - BL Direct - All 6 versions
aacrjournals.org[HTML]Y Sun, XM Tang, E Half, MT Kuo, FA Sinicrope - Cancer research, 2002 - AACR The cyclooxygenase-2 (COX-2) gene encodes an inducible enzyme that converts arachidonic acid to prostaglandins and is up-regulated in colorectal neoplasms. Evidence indicates that COX-2 may regulate apoptosis and can influence the malignant phenotype. Non-steroidal ... Cited by 188 - Related articles - BL Direct - All 4 versions
thelancet.com[HTML]… , CL Watkins, MV Sellers, ES Lowe, Y Sun, ML Liao, K … - The Lancet, 2008 - Elsevier We undertook an open-label phase III study with recruitment between March 1, 2004, and Feb 17, 2006, at 149 centres in 24 countries. 1466 patients with pretreated (≥one platinum-based regimen) advanced non-small-cell lung cancer were randomly assigned with dynamic ... Cited by 221 - Related articles - All 12 versions
Y Sun - Free Radical Biology and Medicine, 1990 - Elsevier ... 77 *McCormick, ML; Oberley, TD; Elwell, JH; Oberley, LW; Sun, Y.; Li, JJ Superoxide dismutase and catalase level during estrogen-induced renal tumorigenesis in Syrian hamster; manuscript submitted for publication. Antioxidant enzymes versus cancer 591 Preneoplastic and ... Cited by 642 - Related articles - All 3 versions
aacrjournals.org[PDF]… Lee, ZY Wang, H Li, L Chen, Y Sun, S Gobbo, DA … - Cancer Epidemiology …, 1995 - AACR Analysis of Plasma and Urinary Tea Polyphenols in Human Subjects1 ... Mao-Jung Lee, Zhi-Yuan Wang, He Li, Laishun Chen, Yang Sun, Steve Gobbo, Douglas A. Balentine, and Chung S. Yane Laboratory for Cancer Research. College of Pharmacy, Rutgers University. ... Cited by 333 - Related articles - All 3 versions
M Moller, RP Viscidi, Y Sun, E Guerrero, PM Hill, F … - Virology, 1992 - Elsevier Transforming proteins E6 and E7 of human papillomaviruses (HPVs) are consistently expressed in HPV-associated cervical cancers. In ELISA with four HPV-16 E6-E7 peptides, patients with HPV-16-associated invasive cervical cancer (group 1) had a greater seroreactivity than ... Cited by 123 - Related articles - All 3 versions
nih.gov[HTML]JD Birkmeyer, Y Sun, SL Wong, TA Stukel - Annals of surgery, 2007 - ncbi.nlm.nih.gov From the *Michigan Surgical Collaborative for Outcomes Research and Evaluation, Department of Surgery, University of Michigan, Ann Arbor, MI; and †Institute for the Clinical Evaluative Sciences and Department of Health Policy, Management and Evaluation, Faculty of Medicine, ... Cited by 109 - Related articles - BL Direct - All 6 versions
… , R Wyatt, N Hernández-Ramos, Y Sun, PD Kwong, WA … - Science, 1998 - sciencemag.org ... CD Rizzuto, R. Wyatt, N. Hernández-Ramos, Y. Sun, Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA. PD Kwong and ... Cited by 554 - Related articles - BL Direct - All 9
umich.edu[PDF]JD Birkmeyer, Y Sun, A Goldfaden, NJO Birkmeyer … - Cancer, 2006 - interscience.wiley.com 1 Michigan Surgical Collaborative for Outcomes Research and Evaluation (M-SCORE), Department of Surgery, University of Michigan, Ann Arbor, Michigan. 2 Institute for the Clinical Evaluative Sciences, To- ronto, Ontario, Canada. 3 Department of Health Policy, Management and ... Cited by 84 - Related articles - BL Direct - All 5 versions
MR Smith, H Kung, SK Durum, NH Colburn, Y Sun - Cytokine, 1997 - Elsevier ... Mark R. Smith a , f1 , Hsiang-fu Kung b , Scott K. Durum c , Nancy H. Colburn d and Yi Sun e. a Intramural Research Support Program, SAIC Frederick, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, MD, 21702, USA. ... Cited by 138 - Related articles - BL Direct - All 4 versions
jbc.org[HTML]… Roy, C Braastad, Y Sun, A Mukhopadhyay, BB … - Journal of Biological …, 2004 - ASBMB Cancer cells are more susceptible to chemotherapeutic agent-induced apoptosis than their normal counterparts. Although it has been demonstrated that the increased sensitivity results from deregulation of oncoproteins during cancer development (Evan, GI, and Vousden, KH (2001) Nature ... Cited by 83 - Related articles - BL Direct - All 4 versions
Y Wang, Y Sun - Current Cancer Drug Targets, 2002 - ingentaconnect.com Abstract: IGF-IR (Insulin-like growth factor receptor 1) is a tetrameric glycoprotein composed of two α and two β subunits. The α subunit localizes extra-cellularly for ligand binding, whereas the β subunit consists of transmembrane chains and a cytoplasmic tyrosine kinase ... Cited by 66 - Related articles - BL Direct - All 2 versions
J Wang, J Wang, Y Sun, W Song, JE Nor, CY Wang, … - Cellular signalling, 2005 - Elsevier The establishment of metastatic bone lesions in prostate cancer (CaP) is a process partially dependent on angiogenesis. Previously we demonstrated that the stromal-derived factor-1 (SDF-1 or CXCL12)/CXCR4 chemokine axis is critical for CaP cell metastasis. In this investigation, ... Cited by 80 - Related articles - All 4 versions
korea.ac.kr[PDF]KM Bockbrader, M Tan, Y Sun - Oncogene, 2005 - nature.com Inhibitor of apoptosis protein (IAP) suppresses apoptosis through binding and inhibiting active caspases-3, -7 and -9 via its baculoviral IAP repeat (BIR) domains. During apoptosis the caspase inhibition by IAPs can be negatively regulated by a mitochondrial protein second ... Cited by 71 - Related articles - BL Direct - All 7 versions
Y Sun - Molecular carcinogenesis, 2006 - interscience.wiley.com The p53 tumor suppressor gene plays a key role in prevention of tumor formation through transcriptional dependent and independent mechanisms. Transcriptional-dependent mechanisms are mainly mediated by p53 regulation of downstream targets, leading to growth arrest and ... Cited by 66 - Related articles - BL Direct - All 8 versions
[CITATION] Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12
G Mazzolini, C Qian, X Xie, Y Sun, JJ Lasarte, M … - Cancer Gene Therapy, 1999 Cited by 67 - Related articles
Y Sun, J Wang, Y Liu, X Song, Y Zhang, … - ASCO Meeting …, 2005 - meeting.ascopubs.org Background: Endostar (rh-endostatin, YH-16) is a new recombinant human endostatin developed by Medgenn Co. Ltd. Pre-clinical study indicates that it can inhibit tumor endothelial cell proliferation, angiogenesis, and tumor growth. Phase I and Phase II studies revealed that ... Cited by 49 - Related articles - All 2 versions
Y Sun, Y Wang, J Zhao, M Gu, R Giscombe, AK Lefvert, … - Lung Cancer, 2006 - Elsevier Inhibitory regulatory functions of B7-H3 and B7-H4 regarding T-cell activation have been reported recently. Little is known about the significance of human B7-H3 and B7-H4 expression in non-small-cell lung cancer (NSCLC), and we conducted the present study to address this ... Cited by 65 - Related articles - All 8 versions
RP Viscidi, Y Sun, B Tsuzaki, FX … - … Journal of Cancer, 1993 - interscience.wiley.com Human papillomavirus (HPV) transforming proteins E6 and E7 are uniformly expressed in HPV-associated cervical cancer. Our objective was to measure antibodies to HPV-16 E6 and E7 proteins in cervical cancer patients using an assay which would detect antibodies to ... Cited by 62 - Related articles - BL Direct - All 3 versions
aacrjournals.org[PDF]… , A De Luca, Y Fu, G Condorelli, Y Sun, N Colburn, B … - Cancer Research, 1994 - AACR According to the two-hit hypothesis of Knudson (1), the develop ment of several human cancers is thought to involve loss of heterozy gosity of putative tumor suppressor genes, several of which are not yet identified (2). Many forms of malignancies have been linked to mutations in the ... Cited by 176 - Related articles - BL Direct - All 3 versions
CS Yang, Y Sun, QU Yang, KW Miller, GY … - … the National Cancer …, 1984 - ncbi.nlm.nih.gov 1. J Natl Cancer Inst. 1984 Dec;73(6):1449-53. Vitamin A and other deficiencies in Linxian, a high esophageal cancer incidence area in northern China. Yang CS, SunY, Yang QU, Miller KW, Li GY, Zheng SF, Ershow AG, Blot WJ, Li JY. ... Cited by 57 - Related articles
aacrjournals.org[PDF]JD Brooks, M Weinstein, X Lin, Y Sun, SS Pin, GS … - Cancer Epidemiology …, 1998 - AACR Abstract Prostate intraepithelial neoplasia (PIN) is a purported prostate cancer precursor lesion and a candidate biomarker for efficacy assessment in prostate cancer chemoprevention trials. Loss of expression of the ~'-class glutathione S-transferase enzyme GSTP1, which ... Cited by 194 - Related articles - BL Direct - All 3 versions
sjweh.fi[PDF]D Dong, G Xu, Y Sun, P Hu - … Journal of Work Environment and Health, 1995 - sjweh.fi A retrospective cohort mortality study was conducted for lung cancer aniong silica and clay brick worliers at 11 refractory plants in China. The cohort included 6266 male workers eniployed before 1962 and followed between 1963 and 1985. The standardized rate ratios (SRR) were ... Cited by 54 - Related articles - View as HTML - BL Direct - All 4 versions
nih.gov[HTML]… , TH Foster, H Gao, Y Sun, X Ouyang, WL … - The Journal of clinical …, 2008 - ncbi.nlm.nih.gov 1 Department of Urology, 2 Department of Pathology, and 3 Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, New York, USA. 4 Urologic University Clinic of Basel, Basel, Switzerland. 5 Center for Advanced ... Cited by 65 - Related articles - All 10 versions
… , J Jackman, HF Kung, NH Colburn, Y Sun - …, 1996 - Oxford Univ Press ... Tissue inhibitor of metalloproteinases-3(TEMP-3), a novel member of TEMP family genes, has been recently cloned and shown to be expressed in preneoplastic but not in neoplastic mouse JB6 epidermal cells (Sun et al. 1994 Cancer Res., 54, 11139). ... Cited by 119 - Related articles - BL Direct - All 5 versions
oxfordjournals.org[HTML]Y Sun, S Goodison, J Li, L Liu, W Farmerie - Bioinformatics, 2007 - Oxford Univ Press Motivation: Accurate prognosis of breast cancer can spare a significant number of breast cancer patients from receiving unnecessary adjuvant systemic treatment and its related expensive medical costs. Recent studies have demonstrated the potential value of gene expression ... Cited by 53 - Related articles - BL Direct - All 11 versions
cell.com[HTML]… , U Mahmood, A Mitchell, Y Sun, R Al-Hashem, LR … - Cancer Cell, 2006 - Elsevier To understand the role of human epidermal growth factor receptor (hEGFR) kinase domain mutations in lung tumorigenesis and response to EGFR-targeted therapies, we generated bitransgenic mice with inducible expression in type II pneumocytes of two common hEGFR mutants ... Cited by 173 - Related articles - All 15 versions
[CITATION] … -blind, randomized, multinational phase III trial of letrozole (Femara) compared to tamoxifen as first-line hormonal therapy for advanced breast cancer
H Mouridsen, Y Sun, M Gershanovich, R Perez-Carrion … - Breast Cancer Res Treat, 2001 Cited by 43 - Related articles
oxfordjournals.org[HTML]Y Xu, Y Sun, L Yao, L Shi, Y Wu, T … - Annals of …, 2008 - Eur Soc Med Oncology Results: The serum 4OHtam concentrations were significantly lower in women with the CYP2D6 *10 homozygous variant T/T genotype than in those with the homozygous wild-type C/C genotype (P = 0.04). Among tamoxifen-treated women, women with the T/T genotype had a ... Cited by 44 - Related articles - All 8 versions
nih.gov[HTML]Y Sun - Neoplasia (New York, NY), 2006 - ncbi.nlm.nih.gov E3 ubiquitin ligases are a large family of proteins that are engaged in the regulation of the turnover and activity of many target proteins. Together with ubiquitin-activating enzyme E1 and ubiquitin-conjugating enzyme E2, E3 ubiquitin ligases catalyze the ubiquitination of a ... Cited by 43 - Related articles - All 10 versions
thelancet.com[HTML]… Luo, J Feng, S Ye, TS Yang, J Xu, Y Sun, H Liang, J … - The lancet oncology, 2009 - Elsevier ... of 302]), fatigue (22% [64 of 297] vs 16% [47 of 302]), hand–foot skin reaction (HFSR ... Patients were monitored for adverse events by use of the National Cancer Institute Common Terminology Criteria for ... The academic investigators (A-LC, Y-KK, ZC, C-JT, SQ, JSK, RL, JF, SY, T ... Cited by 180 - Related articles - All 8 versions
aacrjournals.org[PDF]Y Sun, G Hegamyer, NH Colburn - Cancer research, 1994 - AACR ... Nature (Lond.), 281: 589-591, 1979. 2. Sun. Y., Pommier, Y., and Colburn, NH Acquisition of a growth-inhibitory response to phorbol esler involves DNA damage. Cancer Res., 52: 1907-1915, 1992. 3. Sun. Y..Nakamura. K., Hcgamyer. G. Dong. Z., and Colburn. ... Cited by 109 - Related articles - BL Direct - All 3 versions
[CITATION] Phase 3 study of temsirolimus with letrozole or letrozole alone in postmenopausal women with locally advanced or metastatic breast cancer
LWC Chow, Y Sun, J Jassem, J Baselga, DF Hayes, … - Breast Cancer Res Treat, 2006 Cited by 42 - Related articles
D YE, HUI LI, S QIAN, Y SUN, J ZHENG, Y MA - The Journal of urology, 1998 - Elsevier Studies have shown that the effects of chemotherapy depend on some biochemical mechanisms to induce apoptosis. Many genes are involved in apoptosis modulation, including p53, bcl-2 and bax. We determined the roles of p53 status and the ratio of bcl-2/bax proteins for ... Cited by 41 - Related articles - BL Direct - All 4 versions
Y Sun, K Jurgovsky… - Gene therapy, 1998 - ncbi.nlm.nih.gov ... study. SunY, Jurgovsky K, M?¶ller P, Alijagic S, Dorbic T, Georgieva J, Wittig B, Schadendorf D. ... immunomodulation. Therefore, clinical protocols have been developed to treat cancer patients with cytokine gene-modified tumor cells. ... Cited by 123 - Related articles - BL Direct - All 2 versions