背景回顾：Modern agriculture needs large quantities of phosphate (Pi) fertilisers to obtain high yields. Information on how plants sense and adapt to Pi is required to enhance phosphorus-use efficiency (PUE) and thereby promote agricultural sustainability. 

主要发现：Here, we show that strigolactones(SLs) regulate rice root developmental and metabolic adaptations to low Pi, by promoting efficient Pi uptake and translocation from roots to shoots. 

结果1-低磷-SL合成-PHR2释放-磷饥饿基因表达：Low Pi stress triggers the synthesis of SLs, which dissociate the Pi central signalling module of SPX domain-containing protein (SPX4) and PHOSPHATE STARVATION RESPONSE protein (PHR2), leading to the release of PHR2 into the nucleus and activating the expression of Pi-starvation-induced genes including Pi transporters.  

结果2-SL-D14-SDEL1-SPX4-磷饥饿响应：The SLsynthetic analogue GR24 enhances the interaction between the SL receptor DWARF 14 (D14) and a RING-finger ubiquitin E3 ligase (SDEL1). The sdel mutants have a reduced response to Pi starvation relative to wild-type plants, leading to insensitive root adaptation to Pi. Also, SLs induce the degradation of SPX4 via forming the D14-SDEL1-SPX4 complex. 

结论：Our findings reveal a novel mechanism underlying crosstalk between the SL and Pi signalling networks in response to Pi fluctuations, which will enable breeding of high-PUE crop plants.

现代农业需要大量的磷肥才能获得高产。有关植物是如何感知并适应磷环境的了解，有助于我们提高磷利用效率，促进农业的可持续发展。本文中，作者发现独脚金内酯能够通过促进有效磷的吸收以及从根往地上组织的转运，调节水稻根系响应低磷时的发育和代谢适应。低磷胁迫会诱导独脚金内酯的生物合成，而独脚金内酯会解离磷核心信号模块SPX4和PHR2，从而释放PHR2，后者进入到细胞核并激活磷转运蛋白等磷饥饿诱导基因的表达。独脚金内酯人工合成类似物GR24能够增强独脚金内酯受体D14和E3泛素连接酶SDEL1之间的互作。与野生型植物相比，sdel突变体对磷饥饿的响应降低，从而导致根系对磷不敏感。此外，独脚金内酯会通过形成D14-SDEL1-SPX4复合物，诱导SPX4的降解。本文的研究结果揭示了独脚金内酯和磷信号转导网络之间在响应磷波动时的串扰机制，这为将来高磷利用效率的作物育种提供可能。