Plant immunity suppression via PHR1-RALF-FERONIA shapes the root microbiome to alleviate phosphate starvation

第一作者：Jing Tang

第一单位：湖南大学

第一通讯：Feng Yu

 Abstarct 

背景回顾：The microbiome plays an important role in shaping plant growth and immunity, but few plant genes and pathways impacting plant microbiome composition have been reported.  

微生物组在塑造植物生长和免疫过程中发挥重要作用，但我们对于影响植物微生物组组成的植物基因和通路却所知甚少。

研究基础：In Arabidopsis thaliana, the phosphate starvation response (PSR) was recently found to modulate the root microbiome upon phosphate (Pi) starvation through the transcriptional regulator PHR1.

在拟南芥中，最近的研究发现在磷（Pi）饥饿条件下，磷饥饿响应（PSR）会通过转录调控因子PHR1调整植株根部的微生物组。

结果1：Here, we report that A. thaliana PHR1 directly binds to the promoters of rapid alkalinization factor (RALF) genes, and activates their expression under phosphate-starvation conditions. 

本文中，作者发现PHR1能够直接结合到RALF基因的启动子区，在磷饥饿条件下激活这些基因的表达。

结果2：RALFs in turn suppress complex formation of pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) receptor through FERONIA, a previously-identified PTI modulator that increases resistance to certain detrimental microorganisms. 

RALFs反过来也会抑制病原菌相关分子模式PAMP诱导免疫（PTI）受体的复合物形成，该过程是通过一个之前鉴定为PTI调控子FERONIA蛋白，该蛋白能够增强植株对于某些有害微生物的抗性。

结果3：Suppression of immunity via the PHR1-RALF-FERONIA axis allows colonization by specialized root microbiota that help to alleviate phosphate starvation by upregulating the expression of PSR genes. 

通过PHR1-RALF-FERONIA介导的免疫抑制使得某些专性根微生物群能够在植物根部定殖，从而通过上调PSR基因的表达来缓解植株的磷饥饿。

结论：These findings provide a new paradigm for coordination of host-microbe homeostasis through modulating plant innate immunity after environmental perturbations.

本文的研究结果揭示了一个环境变化后，通过调控植物自身免疫来协调寄主-微生物内稳态的典型范例。

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doi: https://doi.org/10.15252/embj.2021109102

Journal: The EMBO Journal

 Published date: February 11, 2022