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第一作者:Pablo Albertos
第一单位:慕尼黑工业大学
第一通讯:Brigitte Poppenberger
Abstract
背景回顾:Heat stress is a major environmental stress type that can limit plant growth and development. To survive sudden temperature increases, plants utilize the heat shock response, an ancient signaling pathway. Initial results had suggested a role for brassinosteroids (BRs) in this response. Brassinosteroids are growth-promoting steroid hormones whose activity is mediated by transcription factors of the BES1/BZR1 subfamily. 主要发现:Here, we provide evidence that BES1 can contribute to heat stress signaling. 结果1-热胁迫诱导BES1:In response to heat, BES1 is activated even in the absence of BRs and directly binds to heat shock elements (HSEs), known binding sites of heat shock transcription factors (HSFs). 结果2-HSFA1与BES1互作:HSFs of the HSFA1 type can interact with BES1 and facilitate its activity in HSE binding. 结论:These findings lead us to propose an extended model of the heat stress response in plants, in which the recruitment of BES1 is a means of heat stress signaling cross-talk with a central growth regulatory pathway. 摘 要
热胁迫是一个主要的环境胁迫类型,限制植物的生长和发育。为了应对突然的环境升温,植物利用了一个古老的信号通路,即热休克响应。一些初步的研究结果已经揭示了油菜素内酯BR参与了该过程。BR是一类能够促进生长的甾体激素,其生物活性是由转录因子BES1/BZR1亚家族所介导的。本文中,作者的研究表明BES1能够作用于植物的热胁迫信号转导。在响应于热胁迫时,植物中BES1在没有BRs的情况下也能够被激活,并且直接结合热休克原件HSEs,而这些元件则是热休克转录因子HSFs的结合位点。HSFA1类的HSFs能够与BES1发生互作,并且促进其结合HSEs的活性。综上,作者提出了一个植物响应热胁迫的拓展模型,其中BES1的招募是热胁迫信号转导与核心生长调节途径之间交互作用的一种方式。 通讯作者 ** Brigitte Poppenberger **
个人简介: 2004-2006,英国约克大学,博后; 2007-2011年,维也纳大学,讲师; 2011年-至今,维也纳大学,副教授/教授。 研究方向:植物甾体激素油菜素内酯的功能和作用模式。
doi: https://doi.org/10.15252/embj.2021108664
Journal: The EMBO Journal
Published date: January 04, 2022
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