世界最酷的女科学家 （Pardis Sabeti, Cool Super Scientist on Earth）

by Baoyu

很久以来就想与众位博友分享一些我心目中的科学家偶像，从07年就开始关注的伊朗裔美籍遗传学家Pardis Sabeti是我最欣赏的一位，就作为系列博文的开篇吧：

以下是对她的个人特写：

    软摇滚乐队Thousand Days的组建者和主唱，

    在世天才百强榜名列第49位，

    获得有女性诺贝尔奖的欧莱雅杰出女科学家奖（香港科大叶玉如院士曾获此奖），

    世界经济论坛专题讨论主持人，

    麻省学士，牛津硕士，哈佛博士（其导师Eric Lander也是天才级人物，以后的诺奖热门人选），

    开发出人类基因组进化新算法，用以破解疟疾和拉沙热的抗性，

    人类单倍体计划HapMap Project主要参与者，

    博后时主持$600,000的课题，

    现在领衔项目包括$2 million的盖茨-梅琳达基金项目，

       31岁的哈佛助教教职（2007），

    每天平均睡2小时，

Pardis Sabeti语录：

      "Even though I am gregarious, I interact more with [scientific] papers than with people. Deep down, I am just a math geek."

      "My mother crated a summer camp in our house, where she would teach the children and make us do book reports. And my sister, who is 2 years older than me, would teach me and my cousin what she had learned in school."

      And the sleep thing? When Science spoke to Sabeti she was managing "only 2 hours of sleep each night, most of them inside a crumpled blue sleeping bag she keeps under a desk . . ."

有关她的音乐：

With support from the MIT Council for the Arts and a women-in-science program sponsored by L’Oreal, Dr. Sabeti is planning a series of music videos featuring Boston-based science luminaries such as Dr. Lander and artificial intelligence expert Marvin Minsky.The videos, which Dr. Sabeti would like to distribute online, will use pop culture to show that science is cool. Her hope is that young viewers will want to learn more about the people in the videos.

Selected Publications

Sabeti, P. C., D. E. Reich, et al. (2002). "Detecting recent positive selection in the human genome from haplotype structure." Nature 419(6909): 832-7.

The International Haplotype Map Consortium (2005). "A haplotype map of the human genome." Nature 437(7063): 1299-320.

Sabeti, P. C., S. F. Schaffner, et al. (2006). "Positive natural selection in the human lineage." Science 312(5780): 1614-20.

Volkman, S. K., P. C. Sabeti, et al. (2007). "A genome-wide map of diversity in Plasmodium falciparum." Nat Genet 39(1): 113-9.

The International Haplotype Map Consortium (2007). "A second generation human haplotype map of over 3.1 million SNPs." Nature 449(7164): 851-61.

Sabeti, P. C., P. Varilly, et al. (2007). "Genome-wide detection and characterization of positive selection in human populations." Nature 449(7164): 913-8.

Other publications cited

Botchkarev, V. A. and M. Y. Fessing (2005). "Edar signaling in the control of hair follicle development." J Investig Dermatol Symp Proc 10(3): 247-51.

Colosimo, P. F., K. E. Hosemann, et al. (2005). "Widespread parallel evolution in sticklebacks by repeated fixation of Ectodysplasin alleles." Science 307(5717): 1928-33.

WHO (2000). "World Health Organization Lassa fever fact sheet No. 179. ." WHO Geneva.

McCormick, J. B. and S. P. Fisher-Hoch (2002). "Lassa fever." Curr Top Microbiol Immunol 262: 75-109

进一步阅读请参考链接：

FAS Center of Harvard Uni.: Pardis Sabeti

http://sysbio.harvard.edu/csb/research/sabeti.html

Wiki百科Pardis_Sabeti:

http://en.wikipedia.org/wiki/Pardis_Sabeti