在科学网首页看到 过度锻炼会让人上瘾  

 (http://www.sciencenet.cn/htmlnews/2009/8/222647.shtm)

 

      有意思。感觉自己也有点这个趋势。

 

于是找了找文章Behavioral Neuroscience 杂志，09年8月期

 

手工检索。终于找到

 

Running and addiction: Precipitated withdrawal in a rat model of activity-based anorexia.

 

Pages 905-912

 

Kanarek, Robin B.; D’Anci, Kristen E.; Jurdak, Nicole; Mathes, Wendy Foulds

Exercise improves cardiovascular health, strengthens muscles and bones, stimulates neuroplasticity, and promotes feelings of well-being. However, when taken to extremes, exercise can develop into an addictive-like behavior. To assess the addictive potential of exercise, withdrawal symptoms following injections of 1.0 mg/kg naloxone were compared in active and inactive male and female rats. Active and inactive rats were given food for 1 hr or 24 hr/day. Additionally, a group of inactive rats was pair-fed the amount of food consumed on the previous day by food-restricted active rats. Rats fed for 1 hr/day decreased food intake and lost weight. Additionally, food-restricted active rats increased wheel running. There was a direct relationship between the intensity of running and the severity of withdrawal symptoms. Active food-restricted rats displayed the most withdrawal symptoms, followed by active rats given 24-hr access to food. Only minimal withdrawal symptoms were observed in inactive rats. These findings support the hypothesis that exercise-induced increases in endogenous opioid peptides act in a manner similar to chronic administration of opiate drugs. (PsycINFO Database Record (c) 2009 APA, all rights reserved)