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2015新发表的文献:
DNA extracted from saliva for methylation studies of psychiatric traits: Evidence tissue specificity and relatedness to brain.主要结论:
1. 通过DNA甲基化信息,可以用唾液采集来研究精神疾病;
2. 唾液DNA甲基化比血液variance更大
There was more variability in CpG sites from saliva than blood, which may reflect its heterogeneity.
3. 相对血液,唾液DNA甲基化更“象”脑部变化;
Finally, DNA methylation in saliva appeared more similar to patterns from each of the brain regions examined overall than methylation in blood.
http://www.ncbi.nlm.nih.gov/pubmed/25355443
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