phenome的个人博客分享 http://blog.sciencenet.cn/u/phenome

博文

吐口水看脑病?唾液vs血液,哪个更能反映精神病患脑部特征?

已有 3641 次阅读 2014-12-25 18:26 |个人分类:Longi Data|系统分类:科研笔记| 大数据, 表观遗传, 唾液, DNA甲基化, longidata

2015新发表的文献:

DNA extracted from saliva for methylation studies of psychiatric traits: Evidence tissue specificity and relatedness to brain.


主要结论:

1. 通过DNA甲基化信息,可以用唾液采集来研究精神疾病;

2. 唾液DNA甲基化比血液variance更大

There was more variability in CpG sites from saliva than blood, which may reflect its heterogeneity.

3. 相对血液,唾液DNA甲基化更“象”脑部变化;

Finally, DNA methylation in saliva appeared more similar to patterns from each of the brain regions examined overall than methylation in blood.


http://www.ncbi.nlm.nih.gov/pubmed/25355443

 



https://blog.sciencenet.cn/blog-508476-853832.html

上一篇:基于表观遗传学的纵向队列研究:奢侈但是大有可为?
下一篇:表观遗传流行病学队列研究的方法学:还很原始
收藏 IP: 111.194.93.*| 热度|

0

该博文允许注册用户评论 请点击登录 评论 (0 个评论)

数据加载中...
扫一扫,分享此博文

Archiver|手机版|科学网 ( 京ICP备07017567号-12 )

GMT+8, 2024-11-23 06:26

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社

返回顶部