TickingClock的个人博客分享 http://blog.sciencenet.cn/u/TickingClock


the plant journal:松树响应热胁迫的可变剪切“记忆”

已有 938 次阅读 2022-9-29 22:58 |个人分类:每日摘要|系统分类:论文交流

​Integrative analysis in Pinus revealed long-term heat stress splicing memory

第一作者Ying Liu


通讯作者Mónica Meijón


背景回顾:Current scenario of climate change has led to increase number of studies describing main drivers in abiotic stress. Recent findings suggest that alternative splicing (AS) has a critical role in controlling plant response to high temperature. AS is a mechanism that allows organisms to create an assortment of RNA transcripts and proteins using single gene information. 

提出问题However, the most important insights suggested about stress AS could not be rigorously addressed because research has been focused on model species which only covered a narrow phylogenetic and life-cycle spectrum. Thus, AS degree of diversification among more dissimilar taxa in heat response is still largely unknown. 

主要研究To fill this gap, the present study employs a systems biology approach to examine how AS landscape responds and ‘remembers’ from heat stress in conifers, a group which have received little attention even though their position can solve key evolutionary questions. 

结果Contrary to angiosperms, we found that potential intron retention may not be the most prevalent type of AS. Furthermore, our integrative analysis with metabolome and proteome data places splicing as the main source of variation during the response. Finally, we evaluated possible acquired long-term splicing-memory in a diverse subset of events and, although this mechanism seems to be conserved in seed plants, AS dynamics are divergent. 

结论These discoveries reveal the particular way of remembering past temperature changes in long-lived plants and open the door to include species with unique features to determine the extent of conservation in gene expression regulation.


 摘 要 


doi: https://doi.org/10.1111/tpj.15990

Journal: the plant jounral

Published date: September 24, 2022

Víctor Roces, Laura Lamelas, Luis Valledor, María Carbó, María Jesús Cañal, Mónica Meijón. Integrative analysis in Pinus revealed long-term heat stress splicing memory. the plant journal, 2022. DOI: https://doi.org/10.1111/tpj.15990


下一篇:Plant Physiology:ABA响应转录因子Dof介导甜樱桃果实软化的分子机制解析
收藏 IP: 218.2.103.*| 热度|


该博文允许注册用户评论 请点击登录 评论 (0 个评论)


Archiver|手机版|科学网 ( 京ICP备07017567号-12 )

GMT+8, 2022-12-9 04:50

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社