Measurements of seminal plasma proteins ECM1 and TEX101 facilitate the differential diagnosis of azoospermia.

Introduction of different APOE isoforms modulates Aβ peptide aggregation and neurotoxicity after amyloid deposition in mouse brain.

Long-term treatment of obese, insulin-resistant nonhuman primates with a seed-targeting antimiR oligonucleotide against the microRNA-33 family derepresses hepatic expression of miR-33 targets, increases circulating HDL cholesterol, and has a clean safety profile.

Single-cell biophysical properties were used for diagnosing malignant pleural effusions from patients

A new high-throughput measurement technique by Tse et al. (this issue) moves mechanical phenotyping of cells in malignant pleural effusions closer to the clinic.

Recent advances in our understanding of molecular clocks highlight their relevance to human physiology and disease.

New technology permits high-throughput identification and analysis of specific T cell receptors.

Central nervous system–specific chloride extrusion enhancers show promise as therapeutics for neuropathic pain.

Leukemic stem cells that generate AML and CML may reside in distinct niches within the bone marrow microenvironment.

Genetic mutations that affect the nitric oxide pathway and lead to accelerated clotting increase the risk of coronary heart disease.