HIV可以通过母乳喂养感染婴儿，但即使是持续的日常通过乳汁接触病毒，也只有1/10 HIV感染母亲会将病毒传递给婴儿。科学家现在已经发现，其中的奥秘就在于母乳中含有来自B细胞的抗体，可以中和HIV。这项研究已于5月18日发表在《Plos One》，请看《科学家》杂志的报道。 

Breast Milk Antibodies Fight HIV

The anti-HIV antibodies from mothers carrying HIV could be used to help develop a vaccine.

By Megan Scudellari | May 30, 2012

HIV can be transmitted to a child via breastfeeding, but despite this chronic, daily exposure to the virus through breast milk, only 1 in 10 HIV-infected nursing mothers passes the virus to her infant. Scientists now think they know why: antibodies from B cells in mother’s milk neutralize HIV-1, the most common strain of the virus, according to research published earlier this month (May 18) in PLoS One.

Researchers from Duke University isolated B cells from the breast milk of an HIV-infected lactating woman in Malawi 3 days after the birth of her child. They identified two antibodies, CH07 and CH08, that bind and neutralize HIV-1.

The finding could help researchers design an HIV-1 vaccine, the authors said. “Our work helped establish that these B cells in breast milk can produce HIV-neutralizing antibodies, so enhancing the response or getting more mucosal B-cells to produce those helpful antibodies would be useful, and this is a possible route to explore for HIV-1 vaccine development,” author Sallie Permar, an assistant professor of pediatrics and infectious diseases at Duke, said in a press release.

http://the-scientist.com/2012/05/30/breast-milk-antibodies-fight-hiv/