学历及研究简历:

2000年09月- 2004年07月 中国农业大学生物学院 理学学士 生物学

2004年09月- 2010年07月 清华大学生命科学学院 理学博士 生物学

近五年获奖成果和名誉称号：

国家自然科学二等奖（2018，排名第三）

云南省项目（2018）

云南省云岭青年人才”（2017）

近三年主持的国家级或百万以上其他项目：

1、国家自然科学基金委面上项目，31672171，逆境下黄瓜果实苦味形成的分子机理研究，2017/01-2020/12，65万元，主持

2、云南省高层次创新创业团队专项，二倍体马铃薯基因组学与分子设计育种，2019/03-2024/03，1000万元，团队负责人

3、云南省基金项目，马铃薯块茎中龙葵素驯化及调控分子机理研究，2019/01-2021/12，100万元，主持

4、国家重点研发计划“合成生物学”重点专项，2018YFA0901800，合成植物天然产物的微生物细胞工厂构建及其应用示范，2019/07-2024/06，2404万元，课题1负责人

5、国家自然科学基金委面上项目，31972433，马铃薯绿原酸代谢调控分子机制解析，2020/01-2023/12，58万元，主持 

近三年主讲课程（研究生，本科）：

2019-2020学年上 研究生课程 论文写作与指导

2018-2019学年下 本科生课程 生命科学进展（讲座）

代表论文和著作：

    Ma, L., Zhang, C., Zhang, B., Tang, F., Li, F., Liao, Q., Tang, D., Peng, Z., Jia, Y., Gao, M., Guo, H., Zhang, J., Luo, X., Yang, H., Gao, D., Lucas, W.J., Li, C*., Huang, S*., Shang, Y*. 2021. A nonS-locus F-box gene breaks self-incompatibility in diploid potatoes. Nature Communications, 12(1).

         Shang, Y., Huang, S. 2020. Engineering Plant Cytochrome P450s for Enhanced Synthesis of Natural Products: Past Achievements and Future Perspectives. Plant communications, 1(1), 100012-100012.

         Xiong, X., Gou, J., Liao, Q., Li, Y., Zhou, Q., Bi, G., Li, C., Du, R., Wang, X., Sun, T., Guo, L., Liang, H., Lu, P., Wu, Y., Zhang, Z., Ro, D.-K., Shang, Y., Huang, S., Yan, J. 2021. The Taxus genome provides insights into paclitaxel biosynthesis. Nature Plants, 7(8), 1026-+.

       Yang, H.-q., Zhang, B., Ma, L., Shang, Y., Gao, D.-l. 2020. Extraction and Spectroscopic Analysis of Chlorogenic Acid in Diploid Potato. Spectroscopy and Spectral Analysis, 40(12), 3860-3864.

       Zhang, C., Yang, Z., Tang, D., Zhu, Y., Wang, P., Li, D., Zhu, G., Xiong, X., Shang, Y., Li, C., Huang, S. 2021. Genome design of hybrid potato. Cell, 184(15), 3873-+.

1.   Li DW^#, Ma YS^#, Zhou Y^#, Gou JB, Zhong Y,   Han LD, Ovchinnikov S, Ma L, Huang SW, Greisen P*, Shang Y*. A   Structural and Data-driven Approach to Engineering a Plant Cytochrome P450   Enzyme, SCIENCE CHINA Life Science, 2019, 62(7): 873–882.

2.   Shang Y*, Huang SW*. Multi-omics Data-driven Investigations of   Metabolic Diversity of Plant Triterpenoids , Plant Journal, 2018,   97(1): 101-111.

3.   Zhong Y^#, Xue XF^#, Liu ZQ^#, Ma YS, Zeng KW,   Ro DK, Bak S, Huang SW, Zhou Y*, Shang Y*. Developmentally Regulated   Glycosylation of Bitter Triterpenoid in Cucumber by the   UDP-Glucosyltransferase UGT73AM3, Molecular Plant, 2017, 10(7):   1000-1003.

4.   Liu XB^#, Liu YS^#, Huang P^#, Ma YS^#,   Qing ZX^#, Tang Q^#, Cao HF^#, Cheng P, Zhen   YJ, Zhou Y, Liu JF, Tang ZS, Zhuo YX, Zhang YC, Yu LL, Huang JL, Yang P, Peng   Q, Zhang JB, Jiang WK, Zhang ZH, Lin K, Ro DK, Chen XY, Xiong XY*, Shang Y*,   Huang SW*, Zeng JG*. The Genome of Medicinal Plant Macleaya cordata Provides   New Insights into Benzylisoquinoline Alkaloids Metabolism. Molecular Plant,   2017, 10(7), 975-989.

5.   Zhou Y^#, Ma YS^#, Zeng JG^#, Duan LX^#,   Xue XF, Wang SH, Lin T, Liu ZQ, Zeng KW, Zhong Y, Zhang S, Hu Q, Liu M, Zhang   HM, Reed J, Moses T, Liu XY, Huang P, Qing ZX, Liu XB, Tu PF, Kuang HH, Zhang   ZH, Osbourn A, Ro DK, Shang Y*, Huang SW*. Convergence and Divergence   of Bitterness Biosynthesis and Regulation in Cucurbitaceae, Nature Plants,   2016, 2(12): 16183.

6.   Shang Y^#, Ma YS^#, Zhou Y^#, Zhang HM^#,   Duan LX, Chen HM, Zeng JG, Zhou Q, Wang SH, Gu WJ, Liu M, Ren JW, Gu XF,   Zhang SP, Wang Y, Yasukawa K, Bouwmeester HJ, Qi XQ, Zhang ZH, Lucas WJ,   Huang SW*. Biosynthesis, Regulation, and Domestication of Bitterness in   Cucumber, Science, 2014, 346(6213): 1084-1088.

7. Shang Y^#, Yan L^#,   Liu ZQ^#, Mei C^#, Cao Z^#, Xin Q, Wu FQ, Wang   XF, Du SY, Jiang T, Zhang XF, Zhao R, Sun HL, Liu R, Yu YT, Zhang DP*. The   Mg-Chelatase H Subunit of Arabidopsis Antagonizes a Group of WRKY   Transcription Repressors to Relieve ABA-Responsive Genes of Inhibition, Plant   Cell, 2010, 22(6): 1909-1935.

8.   Ma YS^#, Zhou Y^#, Ovchinnikov S, Greisen P, Huang SW, Shang   Y*. New Insights into Substrate Folding Preference of Plant OSCs , Science   Bulletin, 2016, 61(18): 1407-1412.

9.   Zhang CZ^#, Wang P^#, Tang D^#, Yang ZM, Lu F,   Qi JJ, Tawari NR, Shang Y, Li CH, Huang SW*. The Genetic Basis of   Inbreeding Depression in Potato. Nature Genetics, 2019.1.14, 51: 374-378.

10.   Lin K^#, Limpens E^#, Zhang ZH, Ivanov S, Saunders DGO,   Mu DS, Pang E, Cao HF, Cha H, Lin T, Zhou Q, Shang Y, Li Y, Sharma T,   van Velzen R, de Ruijter N, Aanen DK, Win J, Kamoun S, Bisseling T, Geurts R,   Huang SW*. Single Nucleus Genome Sequencing Reveals High Similarity Among   Nuclei of an Endomycorrhizal Fungus. PLoS Genetics, 2014, 10(1):   e1004078.

11.   Qi JJ^#, Liu X^#, Shen D^#, Miao H^#,   Xie BY^#, Li XX^#, Zeng P, Wang SH, Shang Y, Gu   XF, Du YC, Li Y, Lin T, Yuan JH, Yang XY, Chen JF, Chen HM, Xiong XY, Huang   K, Fei ZJ, Mao LY, Tian L, Stadler T, Renner SS, Kamoun S, Lucas WJ, Zhang   ZH, Huang SW*. A Genomic Variation Map Provides Insights into the Genetic   Basis of Cucumber Domestication and Diversity. Nature Genetics, 2013,   45(12): 1510-1515.

12.   Lv J^#, Qi JJ^#, Shi QX, Shen D, Zhang SP, Shao GJ, Li H,   Sun ZY, Weng YQ, Shang Y, Gu XF, Li XX, Zhu XG, Zhang JZ, van Treuren   R, van Dooijeweert W, Zhang ZH, Huang SW*. Genetic Diversity and Population   Structure of Cucumber (Cucumis sativus L.). PLoS One, 2012, 7(10):   e46919.

13.   Fan RC^#, Peng CC^#, Xu YH^#, Wang XF^#,   Li Y, Shang Y, Du SY, Zhao R, Zhang XY, Zhang LY, Zhang DP*. Apple   Sucrose Transporter SUT1 and Sorbitol Transporter SOT6 Interact with   Cytochrome b5 to Regulate Their Affinity for Substrate Sugars. Plant   Physiology, 2009, 150(4): 1880-1901.

14.   Wu FQ^#, Xin Q^#, Cao Z^#, Liu ZQ^#,   Du SY, Mei C, Zhao CX, Wang XF, Shang Y, Jiang T, Zhang XF, Yan L,   Zhao R, Cui ZN, Liu R, Sun HL, Yang XL, Su Z, Zhang DP*. The   Magnesium-Chelatase H Subunit Binds Abscisic Acid and Functions in Abscisic   Acid Signaling: New Evidence in Arabidopsis. Plant Physiology, 2009,   150(4): 1940-1954

15.   Zhu SY^#, Yu XC^#, Wang XJ^#, Zhao R^#,   Li Y, Fan RC, Shang Y, Du SY, Wang XF, Wu FQ, Xu YH, Zhang XY, Zhang   DP*. Two Calcium-Dependent Protein Kinases, CPK4 and CPK11, Regulate Abscisic   Acid Signal Transduction in Arabidopsis. Plant Cell, 2007, 19(10):   3019-3036.

16.   Shen YY^#, Wang XF^#, Wu FQ^#, Du SY, Cao Z, Shang   Y, Wang XL, Peng CC, Yu XC, Zhu SY, Fan RC, Xu YH, Zhang DP*. The   Mg-Chelatase H Subunit is an Abscisic Acid Receptor. Nature, 2006,   443(7113): 823-826

       17. 尚轶，黄三文，黄瓜苦味物质的代谢调控与合成生物学，生命科学，2015, 1091-1094.

        18. 孙鹏博，尚轶，葫芦科植物为何有苦味，大自然，2017, 2.

19. 张慧敏，张雷，马永硕，尚轶，王深浩，杨清，黄三文，调控黄瓜苦味基因Bi的AP2/ERF家族转录因子，园艺学报，2014, 41(4): 672-680.