电解水促进三聚氰胺排泄

来自韩国的研究，

本文的假说是功能水，电解水能促进三聚氰胺中毒后的排泄，为证明这个观点，作者通过建立三聚氰胺中毒动物模型，检测体重、尿液晶体、结石、生物化学和血液学检测、肾脏和膀胱组织学检测等。结果发现，电解水能促进动物的体重增加，同时免疫细胞如淋巴细胞、中性颗粒细胞和单核细胞和脾脏平均重量明显增加。电解水组尿液中晶体显著增加，但膀胱结石形成的几率显著减少。结石的成分100%为三聚氰胺。这是国际上首次研究关于电解水可以促进三聚氰胺排泄的研究。

The melamine excretion effect of the electrolyzed reduced water in melamine-fed mice

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Yang-Suk Yoona, 1, Dong-Heui Kima, 1, Soo-Ki Kimb, Soon-Bong Songa, Young Uhc, Dan Jind, Xu-Feng Qia, Yung-Chien Tenga and Kyu-Jae Leea, e,  , 

a Department of Environmental Medical Biology, Wonju College of Medicine, Yonsei University, Wonju, Gangwon 220-701, Republic of Korea

b Department of Microbiology, Wonju College of Medicine, Yonsei University, Wonju, Gangwon 220-701, Republic of Korea

c Department of Laboratory Medicine, Wonju College of Medicine, Yonsei University, Wonju, Gangwon 220-701, Republic of Korea

d Department of Immunology and Pathogenic Biology, College of Medicine, Yanbian University, Yangi, Jilin 133000, China

e Institute for Poverty Alleviation and International Development, Yonsei University Wonju Campus, Wonju, Gangwon 220-710, Republic of Korea

Received 5 February 2011; 

accepted 26 April 2011. 

Available online 5 May 2011.

Abstract

Our hypothesis is that the intake of functional water, electrolyzed reduced water (ERW) can excrete melamine in body was evoked by melamine-tainted feed (MTF). To address this issue, we investigated the effect of ERW in MTF-mice model by way of body weight gain, incidence of urinary crystals and bladder stone, biochemical and haematological examination, histopathologic finding of kidney and urinary bladder, and the evaluation of bladder stone.

We found that the rate of body weight gain was significantly more increased in MTF + ERW group than MTF + PW group. Accordingly, the number of immunocytes such as leukocyte, neutrophil and monocyte as well as the mean weight of spleen was significantly increased in MTF + ERW group. The incidence of urinary crystals was significantly higher in MTF + ERW group, whereas the incidence of urinary bladder stones was lower in MTF + ERW group (52.4%) than in MTF + PW group (38.1%). Also, urinary crystals were more precipitated in MTF + ERW group than MTF + PW group, and urinary bladder stone consists of 100% melamine. Collectively, our data clearly show that ERW intake is helpful to excrete of melamine in MTF mice model and this is the first report on the melamine excretion and clinically implying the safer fluid remedy for melamine-intoxicated hosts.