专刊题目

Microbiota and Immune System: Crosstalk and Clinical Implications

背景描述

This special issue, curated by hLife, delves into the nuanced relationships between microbiota and the immune system across various host organs, including the gut, skin, lungs， etc. Microbiota are essential for the proper training and development of the host’s immune system. However, disruptions in these critical interactions can precipitate a range of immune-mediated disorders and diseases, such as inflammatory conditions, autoimmune pathologies, and susceptibility to infections. The primary objective of this publication is to deepen the scientific and clinical understanding of the dynamic crosstalk between microbiota and the immune system under both stable and perturbed conditions. By exploring these connections, this issue aims to uncover potential pathways for groundbreaking therapeutic innovations that could transform treatment paradigms. This issue warmly invites contributions in various forms, including original research articles that present new data, comprehensive reviews that synthesize existing knowledge, insightful perspectives that propose new theories, and letters to the editor that debate current views. Commentaries that highlight significant advances or emerging issues in this field are also encouraged. Through this collaborative and interdisciplinary platform, this issue seeks to illuminate the complex interactions that underlie the microbiota-immune interface, enhancing our capacity to manipulate these systems for better health outcomes. 

主题

• Impact of Microbiota on Immune Development: Exploring how bacteria, fungi, viruses, etc., influence the host's innate or adaptive immune system under homeostasis conditions.

• Mechanisms of Microbiota-Immune Dysregulation: Detailed examination of how microbiota-immune interactions contribute to diseases such as inflammatory bowel disease, rheumatoid arthritis, cardiometabolic disease, chronic obstructive pulmonary disease, neuronal disorders, cancer, etc.

• Environmental Influences: Investigating how external factors such as climate, pollution, and lifestyle affect microbiota-immune system interactions.

• Advanced Genomic and Metabolomic Techniques: Utilizing AI-driven models, high-throughput sequencing, and other advanced technologies to study microbiota-immune system dynamics.

• Development of Therapeutic Strategies: Innovating new treatments that target microbiota-immune system interactions for various diseases.

截止日期

2025年1月31日

客座专刊编辑

Jinzhi Duan

Principal Investigator

Organization： Institute of Health and Medicine, Hefei Comprehensive National Science Center, China

Research area: Mucosal immunity

Email: Jinzhi_duan@ihm.ac.cn

Miao Liu

Senior Scientist

Organization： Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, USA

Research area: Oncology research and drug development

Email: mliu0@bwh.harvard.edu

Ruirong Tan

Principal Investigator, Associate Professor

Organization： Translational Chinese Medicine Key Laboratory of Sichuan Province, Sichuan Institute for Translational Chinese Medicine, Sichuan Academy of Chinese Medicine Sciences, China

Research area: Immunopharmacology, cancer therapy

Email: ruirongtanlab@163.com

Tao Liu

Principal Investigator

Organization： School of Medicine, Southeast University, China

Research area: Innate immunity

Email: liut47@126.com

Yanan Sun

Research Fellow

Organization： Boston Medical Center, USA

Research area: Blood disorders

Email: sunyanan2020@gmail.com

Sheng Shu

Associate Research Scientist

Organization： Yale University, USA

Research area: Bacterial cell envelope

Email: sheng.shu@yale.edu

投稿指南

Please submit your paper through our online submission system. All papers will be peer-reviewed. The submission deadline is January 31, 2025. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together. Research articles, review articles, letters, commentaries as well as perspectives are invited.

hLife adopts format-freesubmission. Format-free submission means that, provided you include everything necessary for review and using a consistent citation format, you can submit your paper without needing to worry about formatting your manuscript to meet hLife’s requirements.

Please state in the cover letter that your submission is for the special section of “microbiota and immune system”. Article Publishing Charges (APCs) for accepted papers of hLife will be free before 2025.

提交网站

https://www.editorialmanager.com/hlife

期刊简介

hLife是中国科学院微生物研究所主办，中国生物工程学会，浙江大学陈廷烨大健康学院，西湖大学医学院，上海市免疫治疗创新研究院和广州霍夫曼免疫研究所联合支持，与国际出版商爱思唯尔合作的的健康科学领域综合性英文期刊。

hLife聚焦健康科学领域的前沿进展，旨在促进基础研究与临床应用的融合发展。期刊发表与医学相关各研究领域最新成果，学科领域包括（但不限于）病原生物学、流行病学、生理学、免疫学、结构生物学、疾病监测、肿瘤、药物、疫苗和健康政策等。

2022年成功入选“中国科技期刊卓越行动计划高起点新刊”。

投稿网址：https://www.editorialmanager.com/hlife