专刊题目

Mapping the Battlefield: Spatiotemporal Omics to Decode the Dynamics of Infectious Diseases

背景描述

This Special Issue explores how spatiotemporal omics technologies illuminate the dynamic interplay between pathogens and host tissues during infection. By integrating spatial transcriptomics with other techniques, such as single-cell transcriptomics, proteomics, and metabolomics, researchers can now dissect the molecular orchestration of infection processes at scales ranging from the subcellular to the tissue level. We welcome studies that leverage these tools to uncover spatially resolved host immune responses, tissue damage and repair mechanisms, pathogen invasion strategies, and host-pathogen crosstalk during viral, bacterial, fungal, or parasitic infections. We also encourage resources and methodological innovations for spatiotemporal omics data analysis. By bridging cutting-edge omics with clinical insights, this collection aims to advance precision medicine for infectious diseases. 

关键词

Host-pathogen interactions, Spatial transcriptomics, Infection microenvironment, Immune microenvironment, Infection spatial dynamics, Spatial host-pathogen crosstalk

主题

• Spatial transcriptomics of infection microenvironments

• Spatial mapping of vulnerable host-pathogen interfaces

• Single-cell resolution mapping of pathogen entry and immune evasion

• Spatial dynamics of tissue damage and repair post-infection

• Analytical tools for investigating spatial omics data in the context of infection

稿件类型

Article, Perspective, Letter, Commentary, Resource

截止日期

2025年12月31日

客座专刊编辑

Andrea Cossarizza

Professor

Organization: University of Modena and Reggio Emilia, Italy

Research area: Immune alterations during different human diseases

Email: andrea.cossarizza@unimore.it

Paweł P. Łabaj

Professor

Organization: Jagiellonian University, Poland

Research area: Methodological research in data science and its application in transcriptomics and metagenomics for infectious diseases

Email: pawel.labaj@uj.edu.pl

Zhihua Ou

Associate Professor

Organization: BGI Research Beijing, China

Research area: Elucidate the pathogenesis of acute and chronic infectious pathogens using multi-omics approaches

Email: ouzhihua@genomics.cn

Helder Nakaya

Professor

Organization: University of São Paulo, Brazil

Research area: Employ systems biology approaches to understand and predict the immune response in the context of vaccines and infectious diseases

Email: hnakaya@usp.br

投稿指南

Please submit your paper through our online submission system. All papers will be peer-reviewed. The submission deadline is December 31, 2025. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together. Research articles, letters, resources, commentaries as well as perspectives are invited.

hLife adopts format-free submission. Format-free submission means that, provided you include everything necessary for review and using a consistent citation format, you can submit your paper without needing to worry about formatting your manuscript to meet hLife’s requirements.

Please state in the cover letter that your submission is for the special section of "Mapping the Battlefield: Spatiotemporal Omics to Decode the Dynamics of Infectious Diseases". Article Publishing Charges (APCs) for accepted papers of hLife will be waived before 2026. 

投稿网址

https://www.editorialmanager.com/hlife

期刊简介

hLife 由高福院士、董晨院士和Jules A. Hoffmann教授（2011诺奖获得者）领衔，是中国科学院微生物研究所主办，中国生物工程学会，浙江大学陈廷骅大健康学院，西湖大学医学院，上海市免疫治疗创新研究院和广州霍夫曼免疫研究所联合支持，与国际出版商爱思唯尔合作的健康科学领域综合性英文期刊。

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hLife是一本金色开放获取期刊，月刊出版；2022年成功入选“中国科技期刊卓越行动计划高起点新刊”；2023年11月正式创刊；2024年5月被DOAJ收录；2024年8月被Scopus收录；2024年10月入选“首都科技期刊卓越行动计划——重点英文科技期刊支持项目”；2025年6月入选北京市科委“2025年度支持高水平国际科技期刊建设-强刊提升”项目；2025年8月入选中国科学引文数据库（CSCD）核心库。

hLife实行高标准与高效率并重的同行评审机制：

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2026年前hLife接收的稿件免收文章处理费（APC）。

https://www.sciencedirect.com/journal/hlife