​The interplay between auxin and cytokinins affects facets of plant development as different as ovule formation and lateral root initiation. Moreover, cytokinins favor complexity in the development of Solanum lycopersicum and Cardamine hirsuta compound leaves. Nevertheless, no role has been proposed for cytokinins in patterning the margins of the simple leaves of Arabidopsis thaliana, a process that is assumed to be sufficiently explained by auxin localization. Here, we discuss evidence supporting the hypothesis that cytokinins play a role in simple leaf margin morphogenesis via crosstalk with auxin, as occurs in other plant developmental events. Indeed, mutant or transgenic Arabidopsis plants defective in cytokinin biosynthesis or signaling, or with increased cytokinin degradation have leaf margins less serrated than the wild type.

Interactions involving auxin and/or cytokinins in different plant organs, some of which have been shown to occur in leaves.

生长素和细胞分裂素之间的相互作用影响植物发育的各个方面，比如胚珠形成和侧根起始。此外，细胞分裂素在番茄和碎米荠复叶的发育过程中发挥作用。然而，还没有研究显示细胞分裂素在拟南芥单叶边缘的模式建成中发挥作用，目前认为生长素的定位足以解释该过程。本文中，作者讨论了一些支持细胞分裂素通过与生长素的交联在拟南芥的单叶边缘形态发生中发挥作用的假说的证据，正如其与生长素共同作用于其他发育过程中的机制一样。确实，细胞分裂素生物合成或者信号转导存在缺陷、或是细胞分裂素降解增强的突变体或转基因株系，表现出比野生型叶片锯齿更少的表型。