Nature——微观结构学研究揭示突触囊泡融合的神经分子机制 Summary 1. Crystal structures of the Syt1–SNARE–Cpx–Syt1 complex. 2. Close-up views of the SNARE–Cpx–Syt1 tripartite interface. 3. Probing the interfaces between the SNARE complex and the Syt1 C2B domain ...
Nature neurosci——研究表明新生大脑具有很强的重编程再生能力 Summary 1. Irradiation of cerebella at P1 results in a major loss of the EGL by P3, but growth largely recovers and motor behavior is intact at P30. 2. The EGL is progressively replenished after injury. 3 ...
Cell stem cell—研究发现精神分裂症风险基因位点可能富集于染色质开放区间 Graph summary 1.Mapping Open Chromatin by ATAC-Seq in hiPSCs and Differentiated Neurons 2. Genomic Features of Open Chromatin Peaks during Neuronal Differentiation 3. Enrichment and Prioritizat ...
Nature methods—科学家使用电极微阵列对皮层突出投射进行大规模成像 Title 1. A cortical preparation for planar MEA recordings. 2. Information gathered from action potential waveforms. 3. Extracellular spike waveforms contain synaptic signals indicative of neuronal type. 4. ...
Nature—科学家解析果蝇学习和记忆的脑连接组图谱 Summary 1.Mushroom bodies of a first-instar Drosophila larva. 2.KC connectivity reduces redundancy and optimizes stimulus discrimination. 3. A canonical circuit in every MB compartment. 4.MBON inputs and circ ...