2026 Nobel Prize

北京时间10月5日17时30分许，2026年诺贝尔生理学或医学奖揭晓，该奖项授予Karl Deisseroth、Peter Hegemann、Georg Nagel，以表彰他们在光控离子通道和光遗传学方面的发现。

Peter Hegemann教授和Georg Nagel教授曾在 MDPI 期刊发表文章。在此，我们谨向各位获奖者表示衷心的祝贺。

• 获奖者文章

Peter Hegemann

Humboldt University of Berlin, Germany

Reinvestigation of Absorption Spectroscopic Thermal Dynamics of Archaerhodopsin 3 Based Voltage Sensor QuasAr1

Alfons Penzkofer, Arita Silapetere and Peter Hegemann

Bioengineering 2025, 12(12), 1293

https://doi.org/10.3390/bioengineering12121293

Absorption and Emission Spectroscopic Investigation of the Thermal Dynamics of the Archaerhodopsin 3 Based Fluorescent Voltage Sensor Archon2

Alfons Penzkofer, Arita Silapetere and Peter Hegemann

Int. J. Mol. Sci. 2020, 21(18), 6576

https://doi.org/10.3390/ijms21186576

Photocycle Dynamics of the Archaerhodopsin 3 Based Fluorescent Voltage Sensor QuasAr1

Alfons Penzkofer, Arita Silapetere and Peter Hegemann

Int. J. Mol. Sci. 2020, 21(1), 160

https://doi.org/10.3390/ijms21010160

Absorption and Emission Spectroscopic Investigation of the Thermal Dynamics of the Archaerhodopsin 3 Based Fluorescent Voltage Sensor QuasAr1

Alfons Penzkofer, Arita Silapetere and Peter Hegemann

Int. J. Mol. Sci. 2019, 20(17), 4086

https://doi.org/10.3390/ijms20174086

Absorption and Emission Spectroscopic Investigation of Thermal Dynamics and Photo-Dynamics of the Rhodopsin Domain of the Rhodopsin-Guanylyl Cyclase from the Nematophagous Fungus Catenaria anguillulae

Alfons Penzkofer, Ulrike Scheib, Katja Stehfest and Peter Hegemann

Int. J. Mol. Sci. 2017, 18(10), 2099

https://doi.org/10.3390/ijms18102099

Georg Nagel

University of Würzburg, Germany

Coupling the Cardiac Voltage-Gated Sodium Channel to Channelrhodopsin-2 Generates Novel Optical Switches for Action Potential Studies

Christian vom Dahl, Christoph Emanuel Müller, Xhevat Berisha, Georg Nagel and Thomas Zimmer

Membranes 2022, 12(10), 907

https://doi.org/10.3390/membranes12100907

Characterization and Modification of Light-Sensitive Phosphodiesterases from Choanoflagellates

Yuehui Tian, Shang Yang, Georg Nagel and Shiqiang Gao

Biomolecules 2022, 12(1), 88

Extending the Anion Channelrhodopsin-Based Toolbox for Plant Optogenetics

Yang Zhou, Meiqi Ding, Xiaodong Duan, Kai R. Konrad, Georg Nagel and Shiqiang Gao

Membranes 2021, 11(4), 287

https://doi.org/10.3390/membranes11040287

Mutated Channelrhodopsins with Increased Sodium and Calcium Permeability

Xiaodong Duan, Georg Nagel and Shiqiang Gao

Appl. Sci. 2019, 9(4), 664

https://doi.org/10.3390/app9040664

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