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美国生物化学家
艾尔佛列·古曼·吉尔曼(Alfred Goodman Gilman),1941年7月1日出生于美国,职业是药学和生物化学家,主要成就是发现了G蛋白。
艾尔佛列·古曼·吉尔曼(英语:Alfred Goodman Gilman,1941年7月1日-),美国药学和生物化学家。因发现G蛋白与马丁·罗德贝尔一起分享1994年诺贝尔生理学或医学奖。 [1]
https://pubmed.ncbi.nlm.nih.gov/14993334/
http://www.pubmedplus.cn/P/SearchQuickResult?wd=327b8958-a796-4b93-8619-ba786186349e
Mol Interv
. 2001 Apr;1(1):14-21.
PMID: 14993334
Alfred Goodman Gilman was born in the same year (1941) that his father and Louis Goodman published the first edition of The Pharmacological Basis of Therapeutics. Pharmacology has thus always been part of his life, and in his own career he has focused primarily on cell signaling. For the past twenty years, he has chaired the Department of Pharmacology at UT Southwestern, and his long list of accomplishments includes a Nobel Prize (1994) for his work on G proteins. In 1998, Gilman embarked on his most ambitious program of research yet, bringing dozens of leading investigators from the cell signaling community to Dallas in order to plan out a ten-year project aiming "to understand as completely as possible the relationships between sets of inputs and outputs in signaling cells." Now directing the full-fledged, federally funded Alliance for Cellular Signaling, Gilman stresses that a solid database for constructing a "virtual cell" will depend on extensive collaboration from the entire signaling community. (For a complete Program Summary, and to register for membership in the Alliance, consult www.cellularsignaling.org.) The luminaries that were invited to the Dallas planning meeting, in fact, were greeted at the door with a note from Gilman exhorting them: please check EGO at door.
The enduring legacy of Alfred Gilman senior (1908-1984) to pharmacology and clinical medicine.
J Med Biogr. 2018 Aug;26(3):171-175. doi: 10.1177/0967772016665492. Epub 2016 Sep 28.PMID: 27681058
The Molecular Pharmacology of G Protein Signaling Then and Now: A Tribute to Alfred G. Gilman.
Mol Pharmacol. 2016 May;89(5):585-92. doi: 10.1124/mol.116.104216. Epub 2016 Mar 16.PMID: 26984025
Mov Disord. 2015 Jan;30(1):19-36. doi: 10.1002/mds.26120. Epub 2014 Dec 8.PMID: 25488030 Review.
Alfred Goodman Gilman (1941-2015).
Nature. 2016 Jan 21;529(7586):284. doi: 10.1038/529284a.PMID: 26791713 No abstract available.
David J. Triggle: Medicinal chemistry, to pharmacology, calcium channels, and beyond.
Biochem Pharmacol. 2015 Nov 15;98(2):335-41. doi: 10.1016/j.bcp.2015.07.021. Epub 2015 Jul 20.PMID: 26206197 Review.
Natural language query in the biochemistry and molecular biology domains based on cognition search™.
Summit Transl Bioinform. 2009 Mar 1;2009:32-7.PMID: 21347167 Free PMC article.
01. | 2012 | 1 篇 | 0.467% |
02. | 2006 | 2 篇 | 0.935% |
03. | 2005 | 1 篇 | 0.467% |
04. | 2004 | 1 篇 | 0.467% |
05. | 2003 | 3 篇 | 1.402% |
06. | 2002 | 5 篇 | 2.336% |
07. | 2001 | 1 篇 | 0.467% |
08. | 2000 | 3 篇 | 1.402% |
09. | 1999 | 7 篇 | 3.271% |
10. | 1998 | 13 篇 | 6.075% |
11. | 1997 | 12 篇 | 5.607% |
12. | 1996 | 13 篇 | 6.075% |
13. | 1995 | 7 篇 | 3.271% |
14. | 1994 | 11 篇 | 5.140% |
15. | 1993 | 7 篇 | 3.271% |
16. | 1992 | 8 篇 | 3.738% |
17. | 1991 | 11 篇 | 5.140% |
18. | 1990 | 5 篇 | 2.336% |
19. | 1989 | 9 篇 | 4.206% |
20. | 1988 | 3 篇 | 1.402% |
21. | 1987 | 8 篇 | 3.738% |
22. | 1986 | 5 篇 | 2.336% |
23. | 1985 | 4 篇 | 1.869% |
24. | 1984 | 13 篇 | 6.075% |
25. | 1983 | 4 篇 | 1.869% |
26. | 1982 | 5 篇 | 2.336% |
27. | 1981 | 3 篇 | 1.402% |
28. | 1980 | 4 篇 | 1.869% |
29. | 1979 | 3 篇 | 1.402% |
30. | 1978 | 5 篇 | 2.336% |
31. | 1977 | 8 篇 | 3.738% |
32. | 1976 | 5 篇 | 2.336% |
33. | 1975 | 2 篇 | 0.935% |
34. | 1974 | 3 篇 | 1.402% |
35. | 1973 | 2 篇 | 0.935% |
36. | 1972 | 4 篇 | 1.869% |
37. | 1971 | 4 篇 | 1.869% |
38. | 1970 | 2 篇 | 0.935% |
39. | 1968 | 2 篇 | 0.935% |
40. | 1964 | 1 篇 | 0.467% |
41. | 1963 | 2 篇 | 0.935% |
42. | 1950 | 1 篇 | 0.467% |
43. | 1945 | 1 篇 | 0.467% |
01. | j biol chem | 86 篇 | 40.187% |
02. | proc natl acad sci u s a | 29 篇 | 13.551% |
03. | science | 16 篇 | 7.477% |
04. | methods enzymol | 12 篇 | 5.607% |
05. | adv cyclic nucleotide res | 6 篇 | 2.804% |
06. | biochemistry | 6 篇 | 2.804% |
07. | cell | 6 篇 | 2.804% |
08. | nature | 5 篇 | 2.336% |
09. | mol pharmacol | 4 篇 | 1.869% |
10. | j cyclic nucleotide res | 3 篇 | 1.402% |
01. | 美国 | 114 篇 | 53.271% |
02. | 加拿大 | 2 篇 | 0.935% |
03. | 奥地利 | 1 篇 | 0.467% |
没有聚类出数据 |
01. | Animals | 164 篇 | 76.636% |
02. | GTP-Binding Proteins | 122 篇 | 57.009% |
03. | Adenylyl Cyclases | 108 篇 | 50.467% |
04. | Kinetics | 74 篇 | 34.579% |
05. | Cell Line | 56 篇 | 26.168% |
06. | Molecular Sequence Data | 56 篇 | 26.168% |
07. | Enzyme Activation | 53 篇 | 24.766% |
08. | Guanosine 5'-O-(3-Thiotriphosphate) | 53 篇 | 24.766% |
09. | Guanosine Triphosphate | 53 篇 | 24.766% |
10. | Cattle | 48 篇 | 22.430% |
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