Chitin  Elicitor  Receptor  Kinase  1),  a  lysin  motif  containing  pattern  recognition  receptor  (PRR), perceives  chitooligosaccharides  (COs)  to  mount  immune  and  symbiotic  responses.  However,  CERK1  for  a relatively long time has been regarded as a co-receptor in plant immunity, mainly due to its lack of high binding affinity  to  known  elicitors.  Recent  studies  demonstrated  several  novel  carbohydrates  as  ligands  of  CERK1  in different plant species and recognized CERK1 as a key receptor in plant immunity and symbiosis. This review summarizesJournal: Current Biology

recent knowledge acquired on the role of CERK1 in plant-microbe interactions.

CERK1, more than a co-receptor in plant-microbe interactions

第一作者：杨超

通讯单位：中国农业大学

通讯作者：刘俊

前期背景：CERK (Chitin Elicitor Receptor Kinase 1), a lysin motif containing pattern recognition receptor (PRR), perceives chitooligosaccharides (COs) to mount immune and symbiotic responses. 

CERK1(几丁质激发受体 1)是一种含有模式识别受体（PRR）的裂解基序，它感知壳寡糖（COs）来启动免疫共生反应。

提出问题：However, CERK1 for a relatively long time has been regarded as a co-receptor in plant immunity, mainly due to its lack of high binding affinity to known elicitors. 

然而，CERK1长时间被认为是植物免疫的辅助受体，主要是由于缺乏与已知激发子的高结合亲和力。

研究内容：Recent studies demonstrated several novel carbohydrates as ligands of CERK1 in different plant species and recognized CERK1 as a key receptor in plant immunity and symbiosis. 

最近研究表明，一些新的碳水化合物作为CERK1的配体存在不同植物中，并确认CERK1是植物免疫和共生的关键受体。

结论：This review summarizes recent knowledge acquired on the role of CERK1 in plant-microbe interactions.

该综述总结了近期获取的CERK1在植物-微生物相互作用中的作用。

原文链接：https://nph.onlinelibrary.wiley.com/doi/epdf/10.1111/nph.18074?saml_referrer

作者简历：刘俊

研究方向：植物与微生物分子互作；植物抗病遗传学工作经历

2004.08-2006.12   中科院遗传发育所 博士后

2007.01-2013.05   加州大学戴维斯分校 博士后/项目科学家

2012.02-2021.02   中科院微生物所 研究员

2021.02-至今   中国农业大学教授

教育经历

1999.06 本科毕业于南京农业大学园艺系

2004.06 研究生毕业于南京农业大学生命科学学院，获植物学博士学位

Journal:New Phytologist

Published date:  February 25, 2022