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Nature Plants:13个植物顺式调控元件CRE在基因组上的分布

已有 731 次阅读 2019-11-20 15:42 |个人分类:每日摘要|系统分类:论文交流

The prevalence, evolution and chromatin signatures of plant regulatory elements

First author: Zefu Lu; Affiliations: University of Georgia (佐治亚大学): Athens, USA

Corresponding author: Robert J. Schmitz

Chromatin accessibility and modification is a hallmark of regulatory DNA, the study of which led to the discovery of cis-regulatory elements (CREs). Here, we characterize chromatin accessibility, histone modifications and sequence conservation in 13 plant species. We identified thousands of putative CREs and revealed that distal CREs are prevalent in plants, especially in species with large and complex genomes. The majority of distal CREs have been moved away from their target genes by transposable-element (TE) proliferation, but a substantial number of distal CREs also seem to be created by TEs. Finally, plant distal CREs are associated with three major types of chromatin signatures that are distinct from metazoans. Taken together, these results suggest that CREs are prevalent in plants, highly dynamic during evolution and function through distinct chromatin pathways to regulate gene expression.


通讯:Robert J. Schmitz (http://schmitzlab.genetics.uga.edu)


doi: https://doi.org/10.1038/s41477-019-0548-z

Journal: Nature Plants

Published date: November 18, 2019



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下一篇:Plant Biotechnology Journal:水稻GWAS鉴定了一个新的NLR基因作用于稻瘟病抗性


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