Deep learning for inferring gene relationships from single-cell expression data PNAS December 26, 2019 Significance Accurate inference of gene interactions and causality is required for pathway reconstruction, which remains a major goal for many studies. Here, we take advantage of 2 ...
( https://www.nature.com/articles/s41594-020-0511-8?utm_source=feedburnerutm_medium=feedutm_campaign=Feed%3A+nsmb%2Frss%2Fcurrent+%28Nature+Structural+%26+Molecular+Biology+-+Issue%29) Abstract The SARS-CoV-2 non-structural protein 1 (Nsp1), also referred to as the host shut ...
The gasdermins , a protein family executing cell death and inflammation XJJ 细胞焦亡( pyroptosis) Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 Major cell death subroutines. Mammalian cells exposed ...
A single-cell atlas of the peripheral immune response in patients with severe COVID-19 Nature Medicine Published: 08 June 2020 Abstract There is an urgent need to better understand the pathophysiology of Coronavirus disease 2019 (COVID-19), the global pandemic caused by &n ...
A large-scale binding and functional map of human RNA-binding proteins Nature volume 583 , pages711–719(2020) by: XYM ENCODE是什么? ENCODE 计划全称是 The Encylopedia of DNA Elements ,意在揭开人类基因组功能元件的全面图谱。 该 ...
( https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001989) Abstract Background MicroRNAs (miRNAs) play crucial roles in a variety of biological processes via regulating expression of their target genes at the mRNA level. A number of computational approaches regardin ...
Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap Nature Protocols: Published: 21 January 2019 Abstract Pathway enrichment analysis helps researchers gain mechanistic insight into gene lists generated from genom ...