Orthologs: Genes in different species that evolved from a common ancestral gene by speciation; Paralogs: Genes related by duplication within a genome. Normally, orthologs retain the same function in the course of evolution, whereas paralogs evolve new functions, even if related to the origi ...
UniProt EMBL-EBI and SIB together used to produce Swiss-Prot and TrEMBL, while PIR produced the Protein Sequence Database (PIR-PSD). These two data sets coexisted with different protein sequence coverage and annotation priorities. TrEMBL (Translated EMBL Nucleotide Sequence Data Library) was ...