本招聘信息长期有效。 瑞士科学院院士 Horst Vogel 教授招聘博士后 Postdoc Postions in Prof. Horst Vogel's group (English is blow the Chinese descriptions) 一、招聘岗位 单位介绍 :中国科学院深圳先进技术研究院(先进院)是一所以科研为主的集科研、教育、产业、资本为一体 ...
中科院深圳先进技术研究院招聘(“计算机辅助药物设计 中心 袁曙光课题组) Postdoc/PhD/Master positions in computational biology and modern drug discovery(English is blow) 本招聘信息长期有效。 一、招聘岗位 : 单位介绍:中国科学院深圳先进技术研究院(先进院)是一所以科研为主的 ...
The Royal Swedish Academy of Sciences has decided to award the #NobelPrize in Chemistry 2018 with one half to Frances H. Arnold and the other half jointly to George P. Smith and Sir Gregory P. Winter. Sir Gregory Winter, awarded the #NobelPrize in Chemistry, ...
Crystal structure of the Frizzled 4 receptor in a ligand-free state. Shifan Yang, Yiran Wu, Ting-Hai Xu, Parker W. de Waal, Yuanzheng He, Mengchen Pu, Yuxiang Chen, Zachary J. DeBruine, Bingjie Zhang, Saheem A. Zaidi, Petr Popov, Yu Guo, Gye Won Han, Yang Lu, Kelly Suino-Powell, Shao ...
Chemical Science (2018) doi:10.1039/C8SC01680A full text Identifying a target ligand binding site is an important step for structure-based rational drug design as shown here for G protein-coupled receptors (GPCRs), which are among the most popular drug targets. We applied l ...
Nature Reviews Drug Discovery | Published online 28 Jun 2018; doi:10.1038/nrd.2018.103 https://www.nature.com/articles/nrd.2018.103 Amgen’s erenumab recently secured FDA approval as the first G protein-coupled receptor-targeted antibody. More of these biologics are on the way, de ...
Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go Nature (2018) Abstract G-protein-coupled receptors (GPCRs) form the largest family of receptors encoded by the human genome (around 800 genes). They transduce signals by coupling to a small number of ...
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Nature (2018) Published:13 June 2018 Abstract G-protein-coupled receptors comprise the largest family of mammalian transmembrane receptors. They mediate numerous cellular pathways by coupling with d ...