TickingClock的个人博客分享 http://blog.sciencenet.cn/u/TickingClock

博文

Developmental Cell:荫蔽或温暖条件下,COP1通过促进BES1蛋白降解,限制子叶细胞扩张

已有 499 次阅读 2022-8-5 23:32 |个人分类:每日摘要|系统分类:论文交流

Organ-specific COP1 control of BES1 stability adjusts plant growth patterns under shade or warmth

第一作者Cecilia Costigliolo Rojas

第一单位阿根廷布宜诺斯艾利斯生物化学研究所

通讯作者Jorge J. Casal


 Abstract 

背景回顾Under adverse conditions such as shade or elevated temperatures, cotyledon expansion is reduced and hypocotyl growth is promoted to optimize plant architecture. 


提出问题The mechanisms underlying the repression of cotyledon cell expansion remain unknown.


结果1-BES1Here, we report that the nuclear abundance of the BES1 transcription factor decreased in the cotyledons and increased in the hypocotyl in Arabidopsis thaliana under shade or warmth. Brassinosteroid levels did not follow the same trend. 


结果1-PIF4PIF4 and COP1 increased their nuclear abundance in both organs under shade or warmth. PIF4 directly bound the BES1 promoter to enhance its activity but indirectly reduced BES1 expression. 


结果2-COP1COP1 physically interacted with the BES1 protein, promoting its proteasome degradation in the cotyledonsCOP1 had the opposite effect in the hypocotyl, demonstrating organ-specific regulatory networks. 


结论Our work indicates that shade or warmth reduces BES1 activity by transcriptional and post-translational regulation to inhibit cotyledon cell expansion.


fx1_lrg.jpg


 摘 要 

在荫蔽或高温等不利条件下,子叶扩张减少,下胚轴伸长加速,从而达到最优的植物结构。但是,抑制子叶细胞扩张的分子机制尚不清楚。本文中,作者发现在荫蔽或温暖条件下,拟南芥BES1转录因子在子叶中的核丰度降低,但是在下胚轴中的核丰富度增加。油菜素内酯的水平并没有类似的趋势。在荫蔽或温暖条件下,子叶和下胚轴中PIF4和COP1的核丰度都有所增加。PIF4能够直接结合BES1基因的启动子,以增强其转录活性,但会间接降低BES1的表达。COP1与BES1蛋白发生物理互作,促进其在子叶中经由蛋白酶体途径而降解。但是,COP1在下胚轴中具有与子叶中完全相反的作用,说明了器官特异性的调控网络。本文的研究结果表明,荫蔽或温暖环境会通过转录和翻译后调节降低BES1活性,从而抑制子叶细胞的扩张。




 Jorge J. Casal 


个人简介:

1982年,阿根廷布宜诺斯艾利斯大学,学士;

1987年,阿根廷布宜诺斯艾利斯大学,硕士;

1989年,英国莱斯特大学,博士。


研究方向:连接光受体与植物株型和功能控制的信号转导网络。


doi: https://doi.org/10.1016/j.devcel.2022.07.003


Journal: Developmental Cell

Published date: July 27, 2022


Cite:
Cecilia Costigliolo Rojas, Luciana Bianchimano, Jeonghwa Oh, Sofía Romero Montepaone, Dana Tarkowská, Eugenio G. Minguet, Jonas Schön, Mariano García Hourquet, Timo Flugel, Miguel A. Blázquez, Giltsu Choi, Miroslav Strnad, Santiago Mora-García, David Alabadi, Matias D. Zurbriggen, Jorge J. Casal. Organ-specific COP1 control of BES1 stability adjusts plant growth patterns under shade or warmth. Developmental Cell, 2022. DOI: https://doi.org/10.1016/j.devcel.2022.07.003

p.s. 通讯往期精彩链接:

The Plant Cell:拟南芥由PIF4和ELF3滞后介导的日间温度短期记忆




https://blog.sciencenet.cn/blog-3158122-1350134.html

上一篇:IJBM:小RNA参与植物次生代谢的研究进展
下一篇:The Plant Cell:生长素生物合成的转录激活驱动体细胞的发育重编程
收藏 IP: 218.2.103.*| 热度|

0

该博文允许注册用户评论 请点击登录 评论 (0 个评论)

数据加载中...

Archiver|手机版|科学网 ( 京ICP备07017567号-12 )

GMT+8, 2022-9-26 20:23

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社

返回顶部