2024年7月4日，Elsevier 旗下top期刊《Food Chemistry》在线发表了云南师范大学职业技术教育学院Hong Xiaodi课题组最新研究成果《Superparamagnetic photonic crystals with DNA probes for rapid visual detection of mercury》。云南师范大学职业技术教育学院Hong Xiaodi为通讯作者。合作单位有德国海德堡大学细胞生物学系Department of Cellular Biophysics, 

Max Planck Institute for Medical Research, Heidelberg）、中国科学院昆明植物研究所，瓦格宁根大学的食品安全研究中心(Wageningen University & Research, Wageningen Food Safety Research (WFSR)。

https://www.sciencedirect.com/science/article/abs/pii/S0308814624020041

Abstract

A novel superparamagnetic photonic crystal DNA probe (Fe3O4@SiO2@amino@DNA SPC) was developed to enable rapid visual detection of Hg2+. This unique photonic crystal (PC) was synthesized by combining superparamagnetic nanospheres with DNA probes. The DNA probe, rich in thymine (T), detects mercury ions through base mismatch, resulting in the formation of T–Hg2+–T loop hairpin structures. With the binding of Hg2+ to the probe attached to superparamagnetic nanospheres, the PC structure assembled by these nanospheres, formed by the magnetic field, was changed. This change enhanced the reflection intensity; it could be quantified using a fiber optic spectrometer and was visible to the naked eye. The Fe3O4@SiO2@amino@DNA SPC, specific to Hg2+, exhibited a reflection peak at 679 nm, which intensified with increasing Hg2+ concentration. The reflection intensity increased by 132.58 a.u., and the PC color shifted from red to yellow as the Hg2+ concentration increased from 0.1 μg/L to 1 mg/L.