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Mice mate and development

已有 1078 次阅读 2021-7-24 06:57 |系统分类:科研笔记

  1. Pups are born blind, deaf, and hairless.

  2. Skin pigment develops at 3 days.

  3. Ears develops at day 4.

  4. Hair begins to develop at day 5.

  5. Fully haired at day 7.

  6. Ears open at day 9-10.

  7. Eyes opens at day 12-14. 

  8. Wean at approximately 21 days. 


Reproductive Biology

  1. Six weeks to sexual maturity

  2. 4-5 day estrus cycle

  3. 19-21 day gestation peroid

  4. Average litter size 6-8 pups

  5. Wean at 21-28 days of age

  6. Reproductive lifespan variable


Males

  1. Start breeding at 8 weeks

  2. Up to one year as breeders or studs

  3. Retire at one year        some strains (C57BL/6) fertility decreases at 10 months

  4. Retire if infertile with young females

  5. Rotational vs. same cage stable matings


Females

  1. Start breeding at 7-8 weeks

  2. Expect 2-8 litters

  3. Retire at 6 months after set-up

  4. Retire when litter size drops

  5. Retire if no litters in two months

  6. Hold for two weeks after retirement





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