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[Dev. Biol., 2017]健康、疾病中的DNase
陈淑娴 2021-4-13 19:28
Dnases in health and disease Author: Peter A. Keyel* ABSTRACT DNA degradation is critical to healthy organism development and survival. Two nuclease families that play key roles in development and in disease are the Dnase1 and Dnase2 families. While these two families were initial ...
个人分类: 外文期刊精读|3576 次阅读|没有评论
[EMBO rep., 2018]cGAS-STING通路在癌症发生以及肿瘤治疗中的作用
陈淑娴 2021-4-12 21:43
Role of the cGAS–STING pathway in cancer development and oncotherapeutic approaches Authors: Li Teng Khoo Liuh-Yow Chen* 这是一篇年份较近的阐述cGAS-STING通路和癌症发生以及靶向治疗思路的文章,讲的比较完善,以下是博主精读自翻,作为初学者,如有不正确的地方欢迎指正~ The cyclic GMP- ...
个人分类: 外文期刊精读|7632 次阅读|没有评论
[Front. Immunol., 2018]利用对胞质核酸感知通路的靶向创造肿瘤免疫疗法的新思路【上】
陈淑娴 2021-4-9 15:00
Targeting Cytosolic nucleic Acid-Sensing Pathways for Cancer immunotherapies Authors: Sandra Iurescia*†, Daniela Fioretti† and Monica Rinaldi* The innate immune system provides the first line of defense against pathogen infection though also influences pathways involve ...
个人分类: 外文期刊精读|1977 次阅读|没有评论
[Plos Pathog., 2011] 天然免疫中的DNA感知
陈淑娴 2021-4-8 16:59
Innate Immune Sensing of DNA Author: Shruti Sharma, Katherine A. Fitzgerald* When a pathogen attacks, the immune system rapidly mobilizes host defenses in order to reduce the microbial burden and limit damage to the host . Innate immunity is the first line of defense and ...
个人分类: 外文期刊精读|2441 次阅读|没有评论
[Mediat Inflamm, 2018] STING信号促进细胞凋亡、坏死以及细胞死亡:一篇综述及更新
陈淑娴 2021-4-7 18:15
STING Signaling Promotes Apoptosis, Necrosis, and Cell Death: An Overview and Update Author: Song Liu and Wenxian Guan STING is a newly identified intracellular sensor of foreign and endogenous DNA. STING has been recognized as an activator of immune responses by TBK1/IRF3 and NF-κB ...
个人分类: 外文期刊精读|4153 次阅读|没有评论
[PNAS, 11/2/2020]乙烯响应下TREE1及EIN3合作介导的转录抑制活动会阻碍植株地上部分的生长发育
陈淑娴 2020-11-10 22:15
TREE1-EIN3–mediated transcriptional repression inhibits shoot growth in response to ethylene Author: Likai Wang, et al. Corresponding author:Hong Qiao. PNASfirst published November 2, 2020 Affiliations: Institute for Cellular and Molecular Biology, The University ...
个人分类: 外文期刊精读|5563 次阅读|没有评论
[Science]胚与胚乳之间的分子双向交流在种子发育过程中必不可少(3/END)
陈淑娴 2020-10-21 22:50
A two-way molecular dialogue between embryo and endosperm is required for seed development Author: N. M. Doll, S. Royek, S. Fujita, et al. Corresponding author: G. Ingram. Affiliations: Laboratoire Reproduction et Développement des Plantes, University of Lyon, EN ...
个人分类: 外文期刊精读|4166 次阅读|没有评论
[Science]胚与胚乳之间的分子双向交流在种子发育过程中必不可少(2)
陈淑娴 2020-10-20 15:25
A two-way molecular dialogue between embryo and endosperm is required for seed development Author: N. M. Doll, S. Royek, S. Fujita, et al. Corresponding author: G. Ingram. Affiliations: Laboratoire Reproduction et Développement des Pla ...
个人分类: 外文期刊精读|2686 次阅读|没有评论
[Science]胚与胚乳之间的分子双向交流在种子发育过程中必不可少(1)
陈淑娴 2020-10-19 10:43
A two-way molecular dialogue between embryo and endosperm is required for seed development Author: N. M. Doll, S. Royek, S. Fujita, et al. Corresponding author: G. Ingram. Affiliations: Laboratoire Reproduction et Développement des Plantes, University of Lyon, ENS de ...
个人分类: 外文期刊精读|2829 次阅读|没有评论
[the Plant Journal] DLC1基因编码了B类反应调控因子并且在水稻的减数分裂中起到关键作用
陈淑娴 2020-10-18 17:29
这是一篇 2019 年发表在 the plant journal 的文章,文章中所用到的实验逻辑与方法,和实验室常用的非常相似,在上周的一门必修课程的汇报中我选择了该篇文章进行汇报。本人才疏学浅,希望能和大家一起交流。 这篇文章主要讲的是,作者利用图位克隆 ...
个人分类: 外文期刊精读|3367 次阅读|没有评论

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