Dnases in health and disease Author: Peter A. Keyel* ABSTRACT DNA degradation is critical to healthy organism development and survival. Two nuclease families that play key roles in development and in disease are the Dnase1 and Dnase2 families. While these two families were initial ...
Role of the cGAS–STING pathway in cancer development and oncotherapeutic approaches Authors: Li Teng Khoo Liuh-Yow Chen* 这是一篇年份较近的阐述cGAS-STING通路和癌症发生以及靶向治疗思路的文章，讲的比较完善，以下是博主精读自翻，作为初学者，如有不正确的地方欢迎指正~ The cyclic GMP- ...
Targeting Cytosolic nucleic Acid-Sensing Pathways for Cancer immunotherapies Authors: Sandra Iurescia*†, Daniela Fioretti† and Monica Rinaldi* The innate immune system provides the first line of defense against pathogen infection though also influences pathways involve ...
Innate Immune Sensing of DNA Author: Shruti Sharma, Katherine A. Fitzgerald* When a pathogen attacks, the immune system rapidly mobilizes host defenses in order to reduce the microbial burden and limit damage to the host . Innate immunity is the first line of defense and ...
STING Signaling Promotes Apoptosis, Necrosis, and Cell Death: An Overview and Update Author: Song Liu and Wenxian Guan STING is a newly identified intracellular sensor of foreign and endogenous DNA. STING has been recognized as an activator of immune responses by TBK1/IRF3 and NF-κB ...
TREE1-EIN3–mediated transcriptional repression inhibits shoot growth in response to ethylene Author: Likai Wang, et al. Corresponding author:Hong Qiao. PNASfirst published November 2, 2020 Affiliations: Institute for Cellular and Molecular Biology, The University ...
A two-way molecular dialogue between embryo and endosperm is required for seed development Author: N. M. Doll, S. Royek, S. Fujita, et al. Corresponding author: G. Ingram. Affiliations: Laboratoire Reproduction et Développement des Plantes, University of Lyon, EN ...
A two-way molecular dialogue between embryo and endosperm is required for seed development Author: N. M. Doll, S. Royek, S. Fujita, et al. Corresponding author: G. Ingram. Affiliations: Laboratoire Reproduction et Développement des Pla ...
A two-way molecular dialogue between embryo and endosperm is required for seed development Author: N. M. Doll, S. Royek, S. Fujita, et al. Corresponding author: G. Ingram. Affiliations: Laboratoire Reproduction et Développement des Plantes, University of Lyon, ENS de ...
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