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韩春雨:NBT最新质疑提供了线索

已有 12018 次阅读 2016-11-30 08:04 |系统分类:海外观察

韩春雨又出新闻了。今天我看了《自然网站》,发现那个 David Cyranoski 更新了他原来的报道,增加了韩春雨对 NBT  上最新失败报道的回应。


据报道,韩春雨 stands by his team’s original claims, and that the latest Nature Biotechnology report “provides us some clues as to why others are having problems”. He says that he hopes to submit a scientific paper explaining why others are having difficulty by the end of the year.


也就是说,韩春雨坚持其研究小组最初声称的结果。韩说:最新的NBT失败报告“给我们提供了为什么其他人遇到(重复性)问题的线索“。韩希望在年底以前递交一篇论文,解释为何其他人遇到困难。


韩春雨的新文章自然应该会发给《自然》。


《自然》网站读者好像不愿多发意见,仍然只有我一条外行说 行话的评论。但有一位以色列的研究人员对我的观点表示赞同。Patience is  a virtue.


Dong Liu's team was not discouraged by the detractors in their pursuit of science. Even though they didn't see cleavage activity, instead of throwing in the towel and throwing up their hands, they looked deeper and their curious minds uncovered something interesting. Their results unmistakably verified a key characteristic of the Han NgAgo+gDNA system in zebrafish: PAM-free precise gene targeting with ssDNA guides up to 24nt in length. That was a major step forward.

Han claims that he has successfully replicated his experiments twice or more with commercially available cells. Patience is a virtue. Let's give him a bit more time.




http://www.nature.com/news/updated-ngago-gene-editing-controversy-escalates-in-peer-reviewed-papers-1.21023?WT.mc_id=TWT_NatureNews





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