氢分子医学分享 http://blog.sciencenet.cn/u/孙学军 对氢气生物学效应感兴趣者。可合作研究:sunxjk@hotmail.com 微信 hydrogen_thinker

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一图读懂氢气医学临床研究

已有 4259 次阅读 2015-5-9 18:53 |个人分类:氢气医学临床|系统分类:科研笔记

     国际上关于氢气医学的临床研究已经有19篇研究论文,最近有波黑学者Ostojic SM发表综述对临床研究进行了专门总结,为尽快让大家了解,现将文章中的一个图发给大家,因为这个图中引用了全部氢气医学临床研究的文献。全文内容不久将在科学网和公众号同时推送,敬请期待。

Molecular hydrogen: An inert gas turns clinically effective.

Ostojic SM. Ann Med. 2015.


  • 9. KajiyamaS, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, et al. Supplementationof hydrogen-rich water improves lipid and glucose metabolism in patients withtype 2 diabetes or impaired glucose tolerance. Nutr Res. 2008;28:137–43. (糖尿病)

  • 10. NakaoA, Toyoda Y, Sharma P, Evans M, Guthrie N. Effectiveness of hydrogen rich wateron antioxidant status of subjects with potential metabolic syndrome-an openlabel pilot study. J Clin Biochem Nutr. 2010;46:140–9.(代谢综合症)

  • 11. NakayamaM, Nakano H, Hamada H, Itami N, Nakazawa R, Ito S. A novel bioactivehaemodialysis system using dissolved dihydrogen (H2) produced by waterelectrolysis: a clinical trial. Nephrol Dial Transplant. 2010;25:3026–33.12. (血液透析)

  • Ono H,Nishijima Y, Adachi N, Tachibana S, Chitoku S, Mukaihara S, et al. Improvedbrain MRI indices in the acute brain stem infarct sites treated with hydroxylradical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. Anon-controlled study. Med Gas Res. 2011;1:12. (脑干缺血)

  • 13.KangKM,KangYN,ChoiIB,GuY,KawamuraT,ToyodaY,et al.Effects of drinkinghydrogen-rich water on the quality of life of patients treated withradiotherapy for liver tumors. Med Gas Res. 2011;1:11. (肝癌放射治疗)

  • 14. Ito M,Ibi T, Sahashi K, Ichihara M, Ito M, Ohno K. Open-label trial and randomized,double-blind, placebo-controlled, crossover trial of hydrogen-enriched waterfor mitochondrial and inflammatory myopathies. Med Gas Res. 2011;1:24. (肌肉病)

  • 15. Ono H,Nishijima Y, Adachi N, Sakamoto M, Kudo Y, Nakazawa J, et al. Hydrogen(H2)treatment for acute erythymatous skin diseases. A report of 4 patients withsafety data and a non-controlled feasibility study with H2 concentrationmeasurement on two volunteers. Med Gas Res. 2012;2:14. (皮肤病)

  • 16. Ono H,Nishijima Y, Adachi N, Sakamoto M, Kudo Y, Kaneko K, et al. A basic study onmolecular hydrogen (H2) inhalation in acute cerebral ischemia patients forsafety check with physiological parameters and measurement of blood H2 level.Med Gas Res. 2012;2:21. (脑缺血患者安全性)

  • 17.Ishibashi T, Sato B, Rikitake M, Seo T, Kurokawa R, Hara Y, et al. Consumptionof water containing a high concentration of molecular hydrogen reducesoxidative stress and disease activity in patients with rheumatoid arthritis: anopen-label pilot study. Med Gas Res. 2012;2:27. (类风湿关节炎)

  • 18.SongG,LiM,SangH,ZhangL,LiX,YaoS,etal.Hydrogen-richwater decreases serumLDL-cholesterol levels and improves HDL function in patients with potentialmetabolic syndrome. J Lipid Res. 2013;54: 1884–93. (代谢综合症)

  • 19. Li Q,Kato S, Matsuoka D, Tanaka H, Miwa N. Hydrogen water intake via tube-feedingfor patients with pressure ulcer and its reconstructive effects on normal humanskin cells in vitro. Med Gas Res. 2013;3:20. (皮肤溃疡)

  • 20.Terawaki H, Hayashi Y, Zhu WJ, Matsuyama Y, Terada T, Kabayama S, et al.Transperitoneal administration of dissolved hydrogen for peritoneal dialysispatients: a novel approach to suppress oxidative stress in the peritonealcavity. Med Gas Res. 2013;3:14. (腹膜透析)

  • 21.Yoritaka A, Takanashi M, Hirayama M, Nakahara T, Ohta S, Hattori N. Pilot studyof H2 therapy in Parkinson’s disease: a randomized double- blindplacebo-controlled trial. Mov Disord. 2013;28:836–9. (帕金森病)

  • 22.Matsumoto S, Ueda T, Kakizaki H. Effect of supplementation with hydrogen-richwater in patients with interstitial cystitis/painful bladder syndrome. Urology.2013;81:226–30. (间质性膀胱炎)

  • 23. Xia C,Liu W, Zeng D, Zhu L, Sun X, Sun X. Effect of hydrogen-rich water on oxidativestress, liver function, and viral load in patients with chronic hepatitis B.Clin Transl Sci. 2013;6:372–5. (慢性肝炎)

  • 24.Ostojic SM, Vukomanovic B, Calleja-Gonzalez J, Hoffman JR. Effectiveness oforal and topical hydrogen for sport-related soft tissue injuries. Postgrad Med.2014;126:187–95. (运动相关组织损伤)

  • 最近有关于透析导致的腹膜硬化和银屑病(牛皮癣)




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