博文
2022年诺贝尔生理学或医学奖得主Svante Pääbo的科学贡献
||
2022年诺贝尔生理学或医学奖揭晓！
https://news.sciencenet.cn/news/sub24.aspx?id=3942
https://news.sciencenet.cn/htmlnews/2022/10/487249.shtm
科学网直播
https://weibo.com/l/wblive/p/show/1022:2321324819526436127559
北京时间10月3日下午5点33分许，2022年诺贝尔生理学或医学奖揭晓。瑞典科学家Svante Pääbo获奖，以表彰他“ 在灭绝古人类基因组和人类进化方面的发现”。
https://www.163.com/dy/article/HIP941JN05118KMO.html
详解2022诺贝尔生理学或医学奖：他创立了一门全新学科，揭示人类因何独一无二
https://mp.weixin.qq.com/s/et8G1mnTr73xhH2Tw7-mAA
检索到文献344篇
http://www.pubmedplus.cn/P/SearchQuickResult?wd=9305c979-326b-42d8-9f11-106ad9b0de9f
1. Analysis of candidate genes for lineage-specific expression changes in humans and primates.
Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University , Dag Hammarskjölds väg 20, SE-751 85 Uppsala, Sweden.
J Proteome Res (P 1535-3907 E 1535-3893) H指数：145 2014 年 13 卷 8 期 3596-606 页
PMID：24911366 相似文献
英
汉
Department of Neuroscience, Uppsala University, Uppsala, Sweden.
Physiol Genomics (P 1531-2267 E 1094-8341) H指数：101 2013 年 45 卷 9 期 367-76 页
PMID：23512741 相似文献
英
汉
3. Mitochondrial genome variation and the origin of modern humans.
M Ingman,H Kaessmann,S Pääbo,U Gyllensten
Department of Genetics and Pathology, Section of Medical Genetics, University of Uppsala, Sweden.
Nature (P 0028-0836 E 0028-0836) H指数：1096 2000 年 408 卷 6813 期 708-13 页
PMID：11130070 相似文献
1.分析人类和灵长类谱系特异性表达变化的候选基因。
Cecilia Lindskog、Martin Kuhlwilm、Armaty Davierwala、Ning Fu、Geeta Hegde、Mathias Uhlén、Sanjay Navani、Svante Päbo、Fredrik Pontén
瑞典乌普萨拉大学生命科学实验室免疫学、遗传学和病理学系，地址：瑞典乌普巴拉SE-751 85，Dag Hammarskjölds väg 20。
蛋白质组研究杂志（P 1535-3907 E 1535-3893）H指数：145 2014 年 13卷 8.期 3596-606 页
项目管理编号：24911366相似文献
文摘 内政部链接 美国化学学会
英 汉
2.肉碱-棕榈酰辅酶a转移酶-1B的表达受顺式作用eQTL的影响，这两个选择用于高体重和低体重的鸡品系。
Sojeong Ka、Ellen Markljung、Henrik Ring、Frank W Albert、Mohammad Harun Or Rashid、Per Wahlberg、Pablo M Garcia Roves、Juleen R Zierath、D Michael Denbow、Svante Pääbo、Paul B Siegel、Leif Andersson、Finn Hallbök
瑞典乌普萨拉大学神经科学系。
生理基因组学（P 1531-2267 E 1094-8341）H指数：101 2013 年 45卷 9期 367-76 页
项目管理编号：23512741相似文献
文摘 内政部链接 阿提蓬牌手表
英 汉
3.线粒体基因组变异与现代人类起源。
M Ingman、H Kaessmann、S Paäbo、U Gyllensten
瑞典乌普萨拉大学医学遗传学科遗传学和病理学系。
性质（P0028-0836 E 0028-0836）H指数：1096 2000 年 408卷 6813期 708-13 页
项目管理编号：11130070相似文献
文摘 内政部链接 自然出版集团Ovid Technologies，股份有限公司。
https://pubmed.ncbi.nlm.nih.gov/11130070/
https://pubmed.ncbi.nlm.nih.gov/?term=P%C3%A4%C3%A4bo+S&cauthor_id=11130070
Nature
. 2000 Dec 7;408(6813):708-13.
doi: 10.1038/35047064.
Mitochondrial genome variation and the origin of modern humans
Affiliations expand
PMID: 11130070
DOI: 10.1038/35047064
Erratum in
Nature 2001 Mar 29;410(6828):611
Abstract
The analysis of mitochondrial DNA (mtDNA) has been a potent tool in our understanding of human evolution, owing to characteristics such as high copy number, apparent lack of recombination, high substitution rate and maternal mode of inheritance. However, almost all studies of human evolution based on mtDNA sequencing have been confined to the control region, which constitutes less than 7% of the mitochondrial genome. These studies are complicated by the extreme variation in substitution rate between sites, and the consequence of parallel mutations causing difficulties in the estimation of genetic distance and making phylogenetic inferences questionable. Most comprehensive studies of the human mitochondrial molecule have been carried out through restriction-fragment length polymorphism analysis, providing data that are ill suited to estimations of mutation rate and therefore the timing of evolutionary events. Here, to improve the information obtained from the mitochondrial molecule for studies of human evolution, we describe the global mtDNA diversity in humans based on analyses of the complete mtDNA sequence of 53 humans of diverse origins. Our mtDNA data, in comparison with those of a parallel study of the Xq13.3 region in the same individuals, provide a concurrent view on human evolution with respect to the age of modern humans.
Comment in
Human evolution. A start for population genomics.
Nature. 2000 Dec 7;408(6813):652-3. doi: 10.1038/35047193.PMID: 11130051 No abstract available.
Similar articles
DNA sequence variation in a non-coding region of low recombination on the human X chromosome.
Nat Genet. 1999 May;22(1):78-81. doi: 10.1038/8785.PMID: 10319866
Harvesting the fruit of the human mtDNA tree.
Trends Genet. 2006 Jun;22(6):339-45. doi: 10.1016/j.tig.2006.04.001. Epub 2006 May 4.PMID: 16678300 Review.
Fungal Genet Biol. 2007 Oct;44(10):991-1001. doi: 10.1016/j.fgb.2007.03.005. Epub 2007 Apr 2.PMID: 17493848
Whole-mtDNA genome sequence analysis of ancient African lineages.
Mol Biol Evol. 2007 Mar;24(3):757-68. doi: 10.1093/molbev/msl209. Epub 2006 Dec 28.PMID: 17194802
Mitochondrial DNA and human evolution.
Annu Rev Genomics Hum Genet. 2005;6:165-83. doi: 10.1146/annurev.genom.6.080604.162249.PMID: 16124858 Review.
Cited by
Sci Rep. 2022 Jul 29;12(1):13016. doi: 10.1038/s41598-022-16164-9.PMID: 35906446 Free PMC article.
Sci Rep. 2022 Jun 24;12(1):10747. doi: 10.1038/s41598-022-13856-0.PMID: 35750688 Free PMC article.
Genomes and demographic histories of the endangered Bretschneidera sinensis (Akaniaceae).
Gigascience. 2022 Jun 14;11:giac050. doi: 10.1093/gigascience/giac050.PMID: 35701375 Free PMC article.
Sci Rep. 2022 Apr 26;12(1):6827. doi: 10.1038/s41598-022-10530-3.PMID: 35473946 Free PMC article.
Front Genet. 2022 Mar 24;13:857866. doi: 10.3389/fgene.2022.857866. eCollection 2022.PMID: 35401710 Free PMC article.
Publication types
MeSH terms
Africa
Animals
DNA, Mitochondrial*
Evolution, Molecular*
Genetic Variation*
Genome
Humans
Mitochondria / genetics*
Molecular Sequence Data
Phylogeny
X Chromosome
Substances
Associated data
GENBANK/AF346963
GENBANK/AF346964
GENBANK/AF346965
GENBANK/AF346966
GENBANK/AF346967
GENBANK/AF346968
GENBANK/AF346969
GENBANK/AF346970
GENBANK/AF346971
GENBANK/AF346972
GENBANK/AF346973
GENBANK/AF346974
GENBANK/AF346975
GENBANK/AF346976
GENBANK/AF346977
GENBANK/AF346978
GENBANK/AF346979
GENBANK/AF346980
GENBANK/AF346981
GENBANK/AF346982
GENBANK/AF346983
GENBANK/AF346984
GENBANK/AF346985
GENBANK/AF346986
GENBANK/AF346987
GENBANK/AF346988
GENBANK/AF346989
GENBANK/AF346990
GENBANK/AF346991
GENBANK/AF346992
GENBANK/AF346993
GENBANK/AF346994
GENBANK/AF346995
GENBANK/AF346996
GENBANK/AF346997
GENBANK/AF346998
GENBANK/AF346999
GENBANK/AF347000
GENBANK/AF347001
GENBANK/AF347002
GENBANK/AF347003
GENBANK/AF347004
GENBANK/AF347005
GENBANK/AF347006
GENBANK/AF347007
GENBANK/AF347008
GENBANK/AF347009
GENBANK/AF347010
GENBANK/AF347011
GENBANK/AF347012
GENBANK/AF347013
GENBANK/AF347014
GENBANK/AF347015
GENBANK/D38113
GENBANK/D38114
Related information
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
文献检索分析结果
http://www.pubmedplus.cn/P/SearchQuickResult?wd=ee85202c-7709-4da4-b811-556061dbdbd9
| 01. | 无法确认 | 3 篇 | 0.872% |
| 02. | 2022 | 7 篇 | 2.035% |
| 03. | 2021 | 5 篇 | 1.453% |
| 04. | 2020 | 10 篇 | 2.907% |
| 05. | 2019 | 10 篇 | 2.907% |
| 06. | 2018 | 6 篇 | 1.744% |
| 07. | 2017 | 10 篇 | 2.907% |
| 08. | 2016 | 14 篇 | 4.070% |
| 09. | 2015 | 11 篇 | 3.198% |
| 10. | 2014 | 16 篇 | 4.651% |
| 11. | 2013 | 10 篇 | 2.907% |
| 12. | 2012 | 10 篇 | 2.907% |
| 13. | 2011 | 11 篇 | 3.198% |
| 14. | 2010 | 13 篇 | 3.779% |
| 15. | 2009 | 9 篇 | 2.616% |
| 16. | 2008 | 10 篇 | 2.907% |
| 17. | 2007 | 10 篇 | 2.907% |
| 18. | 2006 | 14 篇 | 4.070% |
| 19. | 2005 | 15 篇 | 4.360% |
| 20. | 2004 | 15 篇 | 4.360% |
| 21. | 2003 | 11 篇 | 3.198% |
| 22. | 2002 | 8 篇 | 2.326% |
| 23. | 2001 | 8 篇 | 2.326% |
| 24. | 2000 | 8 篇 | 2.326% |
| 25. | 1999 | 10 篇 | 2.907% |
| 26. | 1998 | 8 篇 | 2.326% |
| 27. | 1997 | 10 篇 | 2.907% |
| 28. | 1996 | 16 篇 | 4.651% |
| 29. | 1995 | 10 篇 | 2.907% |
| 30. | 1994 | 8 篇 | 2.326% |
| 31. | 1993 | 6 篇 | 1.744% |
| 32. | 1992 | 2 篇 | 0.581% |
| 33. | 1991 | 6 篇 | 1.744% |
| 34. | 1990 | 2 篇 | 0.581% |
| 35. | 1989 | 6 篇 | 1.744% |
| 36. | 1988 | 2 篇 | 0.581% |
| 37. | 1987 | 3 篇 | 0.872% |
| 38. | 1986 | 3 篇 | 0.872% |
| 39. | 1985 | 3 篇 | 0.872% |
| 40. | 1983 | 2 篇 | 0.581% |
| 41. | 1981 | 2 篇 | 0.581% |
| 01. | proc natl acad sci u s a | 43 篇 | 12.500% |
| 02. | nature | 41 篇 | 11.919% |
| 03. | science | 28 篇 | 8.140% |
| 04. | curr biol | 18 篇 | 5.233% |
| 05. | mol biol evol | 18 篇 | 5.233% |
| 06. | am j hum genet | 11 篇 | 3.198% |
| 07. | nucleic acids res | 11 篇 | 3.198% |
| 08. | plos one | 10 篇 | 2.907% |
| 09. | cell | 9 篇 | 2.616% |
| 10. | nat genet | 9 篇 | 2.616% |
| 01. | 德国 | 229 篇 | 66.570% |
| 02. | 美国 | 67 篇 | 19.477% |
| 03. | 中国 | 34 篇 | 9.884% |
| 04. | 英国 | 28 篇 | 8.140% |
| 05. | 俄罗斯 | 25 篇 | 7.267% |
| 06. | 瑞典 | 18 篇 | 5.233% |
| 07. | 法国 | 15 篇 | 4.360% |
| 08. | 日本 | 13 篇 | 3.779% |
| 09. | 加拿大 | 11 篇 | 3.198% |
| 10. | 西班牙 | 11 篇 | 3.198% |
| 01. | 中国上海 | 20 篇 | 5.814% |
| 02. | 中国北京 | 14 篇 | 4.070% |
| 03. | 中国昆明 | 2 篇 | 0.581% |
| 04. | 中国济南 | 1 篇 | 0.291% |
| 05. | 中国广州 | 1 篇 | 0.291% |
| 06. | 中国兰州市 | 1 篇 | 0.291% |
| 01. | Humans | 255 篇 | 74.128% |
| 02. | Animals | 254 篇 | 73.837% |
| 03. | Molecular Sequence Data | 112 篇 | 32.558% |
| 04. | Base Sequence | 101 篇 | 29.360% |
| 05. | DNA, Mitochondrial | 99 篇 | 28.779% |
| 06. | Evolution, Molecular | 88 篇 | 25.581% |
| 07. | Phylogeny | 87 篇 | 25.291% |
| 08. | Sequence Analysis, DNA | 69 篇 | 20.058% |
| 09. | Male | 64 篇 | 18.605% |
| 10. | Fossils | 63 篇 | 18.314% |
https://blog.sciencenet.cn/blog-280034-1357862.html
上一篇：诺奖成果 很多是普通的科研工作
下一篇：书画新作 77期 草体书法
