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最近来自澳大利亚和伊朗的学者在《医学气体研究》杂志发表文章,提出根据目前氢气生物医学和神经精神疾病的研究证据,推测氢气可以治疗双向障碍和精神分裂症。其实,我们曾经进行过抑郁症方面的研究,至少在动物实验水平上,确实发现氢气对抑郁症具有很好的治疗效果,不过由于参与研究的学者因病谢世没有及时发表这一研究结果,成为很大的遗憾。可以免费下载全文:
http://www.medicalgasresearch.com/
Molecularhydrogen: an overview of its neurobiologicaleffects and therapeutic potential for bipolar disorder and schizophrenia
Hydrogengas is a bioactive molecule that has a diversity of effects, includinganti-apoptotic, anti-inflammatoryand anti-oxidative properties; these overlap with the process of
neuroprogressionin major psychiatric disorders. Specifically, both bipolar disorder and schizophreniaare associated with increased oxidative and inflammatory stress. Moreover,lithiumwhich is commonly administered for treating bipolar disorder has effects onoxidative stressand apoptotic pathways, as do valproate and some atypical antipsychotics fortreating schizophrenia.Molecular hydrogen has been studied pre-clinically in animal models for the
treatmentof some medical conditions including hypoxia and neurodegenerative disorders, and there are intriguing clinical findings in neurological disorders includingParkinson’s
disease.Therefore, it is hypothesized that administration of hydrogen molecule may have potentialas a novel therapy for bipolar disorder, schizophrenia, and other concurrent disorderscharacterized by oxidative, inflammatory and apoptotic dysregulation.
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