贺建奎的博客分享 http://blog.sciencenet.cn/u/jiankuihe 免疫组库测序,单细胞基因组学

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我的新书 "Modularity"

已有 7039 次阅读 2011-3-11 15:31 |系统分类:论文交流| network, complex, modularity

应Lambert Academic Publishing之邀,我写的书 Modularity: The Principle of Evolution in Complex Systems今天出版了。
此书总结了我数年来在复杂网络,金融物理,和免疫系统进化方面的工作。主题围绕着“模块化” (modularity)展开。此书的核心是提出了生物进化中的模块化定律。
Modularity, understanding systems as the combination of separated components, is a prevalent concept in biology, social science and engineering design. This book offers a general theoretical model of emergence of modularity during evolution in changing environments. Evidences from protein interaction network and protein domain network support this theory as a general law of evolution in complex systems. Applying it to animal development, this theory appears to provide an explanation for the occurrence and timing of the Cambrian explosion. Applying it to trade networks, this theory predicts that globalized economy is more sensitive to recessions. This book also introduces a quantitative measure of hierarchy, a statistical method to predict the dominant flu strain and the first theoretical model to explain the bacterial acquired immunity (CRISPR). The information in the book should help shed some light in the study of complex systems, flu vaccine, and bacterial antibiotic resistance.
购买链接:
http://www.amazon.com/Modularity-principle-evolution-complex-systems/dp/3844311416

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