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结核人群肺癌危险研究动态和化学、药物知识发现

已有 3121 次阅读 2011-1-2 14:51 |个人分类:知识发现|系统分类:论文交流| 化学, 人群, 肺癌, 药物, 结核

http://scienceblog.com/41428/study-finds-evidence-of-increased-lung-cancer-risk-among-tuberculosis-patients/

 

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

 

Start A-Literature C-Literature B-list Filter Literature
  A-query: lung cancer risk
C-query: tuberculosis
The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 384 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 20954 and can be accessed from the start page after you leave this session. There are 1908 terms on the current B-list (521 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin.

To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

 

 

id # 20954 started Sat Jan 1 23:46:35 2011
Max_citations: 50000
Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
20954 Search ARROWSMITH A
A_query_raw: lung cancer risk Sat Jan 1 23:47:09 2011

A query = lung cancer risk started Sat Jan 1 23:47:15 2011
A query resulted in 21471 titles
20954 Search ARROWSMITH C
C_query_raw: tuberculosis Sat Jan 1 23:47:31 2011

C: tuberculosis 188094

A: pubmed_query_A 21471

AC: ( lung cancer risk ) AND ( tuberculosis ) 384

C query = tuberculosis started Sat Jan 1 23:47:32 2011
C query resulted in 50000 titles
A AND C query resulted in 384 titles
21875 B-terms ready on Sat Jan 1 23:53:25 2011

Sem_filter:
Chemicals & Drugs
1908 B-terms left after filter executed Sun Jan 2 02:25:27 2011

B-list on Sun Jan 2 02:33:26 2011
1 highly active antiretroviral
2 docetaxel
3 paclitaxel
4 cox-2
5 active antiretroviral
6 transferase m1
7 vntr
8 carboplatin
9 transferase m1 t1
10 study docetaxel
11 fluorodeoxyglucose
12 fluorodeoxyglucose positron emission
13 receptor gene polymorphism
14 surfactant protein a
15 antiretroviral
16 nucleotide polymorphism
17 18f fluorodeoxyglucose
18 dna glycosylase
19 irinotecan
20 18f fluorodeoxyglucose positron
21 surfactant protein
22 sirolimus
23 tobacco control
24 oxidative dna
25 number tandem
26 n acetyltransferase nat2
27 endothelial growth factor
28 cytokine gene
29 etoposide
30 oxidative dna damage
31 mycophenolate mofetil
32 d-glucose positron emission
33 m1 t1
34 fluorodeoxyglucose uptake
35 phosphatidylinositol 3-kinase akt
36 alpha methylacyl coa
37 methylacyl coa racemase
38 clarithromycin
39 argon plasma coagulation
40 vegf
41 single nucleotide
42 minisatellite
43 f-18-fluorodeoxyglucose
44 ofloxacin
45 tyrosine kinase inhibitor
46 tacrolimus
47 polymorphism dna
48 idiopathic cd4
49 denaturing gradient gel
50 metalloproteinase-1
51 il-10
52 atomic bomb
53 vitamin d receptor
54 mycophenolate
55 bronchial carcinoid
56 polymorphism intron
57 inhaled corticosteroid
58 tobacco smoke risk
59 highly active
60 receptor polymorphism
61 chemokine
62 bleomycin induced pulmonary
63 dna adduct
64 phase study docetaxel
65 contrast enhanced
66 n acetyltransferase
67 budesonide
68 anti tnf
69 bronchial stump
70 interleukin-10
71 bleomycin induced
72 polymorphism cytochrome
73 matrix metalloproteinase-1
74 south african gold
75 smoking alcohol
76 t polymorphism
77 matrix metalloproteinase
78 pegylated liposomal doxorubicin
79 epoxide hydrolase
80 pseudogene
81 cisplatin
82 exposure silica
83 papillary thyroid
84 ganciclovir
85 d dimer
86 genetic polymorphism glutathione
87 silica dust
88 etoposide cisplatin
89 wood smoke exposure
90 cytokine gene polymorphism
91 il-12
92 fluoro-2-deoxy d-glucose
93 aromatic dna adduct
94 fludarabine
95 smoke risk
96 carboplatin paclitaxel
97 environmental tobacco smoke
98 differentiated thyroid
99 arylamine n acetyltransferase
100 african gold
101 uracil dna glycosylase
102 tobacco smoke
103 3-kinase akt pathway
104 genetic polymorphism cytochrome
105 anca associated
106 fibrin glue
107 cancer diesel exhaust
108 topotecan
109 uracil dna
110 cpg
111 inflammatory cytokine
112 statin
113 small cell bronchial
114 emission tomography f-18-fluorodeoxyglucose
115 diagnosis bronchial
116 coa racemase
117 serum tumor marker
118 phosphatidylinositol 3-kinase
119 matrix metalloproteinase-2
120 cisplatin versus
121 bisphosphonate
122 bronchial epithelial cell
123 cytokine level
124 antioxidant defence
125 tumor marker lung
126 central airway
127 didanosine
128 cyclooxygenase-2
129 cell bronchial
130 fumonisin
131 glutathione s-transferase m1
132 codon
133 liquid chromatography tandem
134 drug discovery
135 green tea
136 s transferase mu
137 papillary microcarcinoma thyroid
138 antiphospholipid
139 ambisome
140 cytokine gene expression
141 telomerase activity
142 fluoro-2-deoxy d-glucose positron
143 igfbp-3
144 atomic bomb survivor
145 adjuvant treatment
146 bronchial lesion
147 tissue inhibitor metalloproteinase
148 cigarette smoke
149 tiotropium
150 polymorphism cytochrome p450
151 anca
152 dna typing
153 imipenem
154 map kinase
155 smoke free
156 green tea extract
157 nucleotide polymorphism first
158 liposomal amphotericin
159 exposed silica
160 cyclooxygenase-2 expression
161 tobacco epidemic
162 tobacco smoke exposure
163 japanese atomic bomb
164 pro apoptotic
165 neuron specific enolase
166 zidovudine
167 factor binding protein
168 tumor marker
169 nucleotide polymorphism analysis
170 p38 mapk
171 matrix metalloproteinase-9
172 peroxisome proliferator activated
173 taxane
174 tnf alpha
175 glutathione s transferase
176 proliferator activated receptor
177 antiphospholipid antibody
178 liposomal amphotericin b
179 cytokine plasma
180 cd4
181 molecular weight heparin
182 smoke exposure
183 c polymorphism
184 polymorphism glutathione
185 d receptor
186 dmard
187 mannose binding lectin
188 dna alkyltransferase
189 surfactant protein d
190 cyfra carcinoembryonic antigen
191 metastatic hepatocellular
192 infection injecting drug
193 reactive nitrogen
194 paraffin embedded tissue
195 epitope
196 paraffin embedded
197 mitoxantrone
198 urokinase receptor
199 association allergy
200 mefloquine
201 cytokine expression
202 transcriptase polymerase chain
203 mannose binding
204 micronutrient
205 diesel exhaust exposed
206 dna vaccine
207 p53 protein
208 cyclosporine
209 exposure tobacco smoke
210 shock protein gene
211 gel microdrop
212 mpo
213 smoking alcohol drinking
214 il-8
215 ciprofloxacin
216 bcl-2 protein
217 lupus anticoagulant
218 quinone oxidoreductase
219 transferase mu
220 oligonucleotide microarray
221 ribavirin
222 histidine triad gene
223 wood smoke
224 coal dust
225 pro gastrin releasing
226 beta catenin
227 fragile histidine triad
228 cladribine
229 hpv dna
230 low cd4
231 b natriuretic peptide
232 cdna
233 dna ligase
234 tgf beta signaling
235 presentation pneumocystis carinii
236 etoposide cisplatin chemotherapy
237 18-fluorodeoxyglucose positron emission
238 cd40-cd40 ligand
239 role nitric oxide
240 cytochrome p450
241 t helper cytokine
242 growth factor receptor
243 value 18f fluorodeoxyglucose
244 antioxidant enzyme
245 cd4 t
246 glutathione s
247 tumor marker cea
248 hdl
249 sentinel
250 prevalence tobacco
251 serum carcinoembryonic antigen
252 ligase
253 intron
254 polymorphism first intron
255 mammalian target rapamycin
256 crack cocaine
257 conjugate vaccine
258 ofloxacin induced
259 ntp technical
260 neopterin a
261 heterocyclic amine
262 glutathione s-transferase
263 polymorphism glutathione s-transferase
264 pro brain natriuretic
265 cytokine patient
266 heat shock protein
267 racemase
268 versus paclitaxel
269 platinum
270 tnf
271 interleukin-8
272 dna adduct human
273 interleukin-1 receptor antagonist
274 nitinol stent
275 interleukin-18
276 hla dqa1
277 retroviral vector
278 formamidopyrimidine dna glycosylase
279 interleukin-2 receptor
280 antineutrophil cytoplasmic antibody
281 cytokine
282 uranium mining
283 lipocalin
284 growth factor binding
285 chemokine expression
286 arylamine
287 paraffin
288 rapamycin
289 protein gene polymorphism
290 gen
291 transplantation hla
292 silica dust exposure
293 effect tobacco
294 vitamin d
295 smoke a
296 dna non small
297 exposure tobacco
298 bronchial biopsy
299 treated fludarabine
300 human bronchial
301 splice
302 mapk
303 catenin
304 t helper
305 radioiodine
306 osteopontin
307 hnrnp
308 epoxide
309 telomerase
310 acrylonitrile
311 exposed silica dust
312 smoke
313 ts-1
314 igf i igf
315 sulfotransferase
316 analysis aromatic dna
317 adhesion molecule-1
318 polycyclic aromatic hydrocarbon
319 respirable coal dust
320 bronchial brushing
321 timp-1
322 visceral adipose tissue
323 untranslated region
324 vitamin d metabolite
325 tea polyphenol
326 diesel
327 polycyclic aromatic
328 sir
329 baseline characteristic
330 tumor necrosis factor
331 lipid peroxidation antioxidant
332 cytochrome p450 2e1
333 myeloperoxidase
334 therapy thalidomide
335 uptake 18f fluorodeoxyglucose
336 mitogen activated
337 shuttle vector
338 tgf beta1
339 galactomannan
340 plasma dna
341 raf-1
342 nuclear factor kappab
343 pigment epitheliopathy
344 mitogen activated protein
345 serum copper zinc
346 versus etoposide
347 alpha crystallin
348 enzyme linked
349 tobacco non
350 reverse transcriptase polymerase
351 based vaccine
352 carbon nanotube
353 diesel exhaust particle
354 inducible nitric oxide
355 level cea
356 adverse drug
357 18f fluorodeoxyglucose uptake
358 cytosolic phospholipase a2
359 copper nickel
360 plasminogen activator inhibitor
361 mrna human
362 growth factor beta1
363 human leukocyte antigen
364 bleomycin
365 vitamin mineral supplementation
366 cyclophosphamide doxorubicin
367 alpha antagonist
368 pneumococcal vaccine
369 expression inducible nitric
370 iron foundry
371 carcinoembryonic antigen
372 roxithromycin
373 serum galactomannan
374 heteroduplex
375 induced cytokine
376 acetyltransferase
377 thalidomide
378 heparin induced thrombocytopenia
379 airborne
380 neopterin
381 interleukin-10 production
382 transactivator
383 molecular chaperone
384 antigen sputum
385 il-6
386 tobramycin
387 kinase inhibitor
388 alternatively spliced
389 polyphenol
390 complementary alternative
391 tissue inhibitor
392 brain natriuretic peptide
393 3-kinase
394 ku
395 based blood test
396 polycyclic
397 cyclooxygenase
398 cyclophosphamide doxorubicin vincristine
399 metal lung
400 gastrin releasing peptide
401 antineutrophil
402 polymorphism untranslated region
403 ion trap
404 shock protein
405 intercellular adhesion molecule-1
406 urban rural
407 h quinone oxidoreductase
408 interleukin receptor
409 specific enolase nse
410 central airway obstruction
411 thrombomodulin
412 placoid pigment epitheliopathy
413 tandem
414 ethanol injection
415 multifocal placoid pigment
416 fluoro d-glucose
417 diesel exhaust
418 reverse transcriptase
419 admitted
420 nitric oxide synthase
421 p selectin
422 papillary mucinous
423 silicone breast
424 hepatocyte growth factor
425 metalloproteinase
426 interleukin-2 interferon
427 cea
428 tobacco
429 hbsag
430 hypoxia inducible factor
431 creb
432 c kit
433 murine model
434 oncoprotein
435 rural urban
436 oxide synthase gene
437 interleukin-1 beta
438 serum paraoxonase arylesterase
439 angiogenesis inhibitor
440 eicosanoid pathway
441 effect tobacco smoke
442 macrophage derived chemokine
443 marijuana
444 m csf
445 endonuclease
446 epitope vaccine
447 interferon gamma
448 murine lung
449 level cytokine
450 p h quinone
451 receptor family
452 phytohaemagglutinin
453 aromatic hydrocarbon
454 reactive nitrogen species
455 natriuretic peptide level
456 effect cigarette
457 stop smoking
458 tobacco alcohol
459 troponin
460 kinase signaling
461 novel vaccine
462 factor receptor lung
463 low dose methotrexate
464 adduct
465 triplex
466 laminin
467 prognostic indicator
468 pneumocystis carinii
469 oxygen radical
470 bronchial wash
471 transcription factor
472 multidrug transporter
473 interleukin-2
474 quartz
475 vaccine a
476 cxc chemokine
477 melanoma antigen
478 tissue inhibitor metalloproteinase-1
479 angiotensin receptor
480 azathioprine
481 tc-99m
482 aspirin ibuprofen
483 11beta hydroxysteroid dehydrogenase
484 i igf
485 arsenic drinking water
486 pollutant
487 renin angiotensin
488 nad p h
489 intron human
490 oxidative damage
491 cytokine cytokine
492 omeprazole
493 udp
494 cimetidine
495 antimicrobial
496 igf i
497 thymidylate
498 exhaust
499 hard metal
500 adjuvant
501 calcitriol
502 airborne particle
503 tgf beta
504 angiogenic
505 cysteine proteinase
506 human t lymphotropic
507 sulindac sulfone
508 antifungal
509 receptor tyrosine kinase
510 transferase t1 m1
511 deoxyglucose
512 eicosanoid
513 century
514 antifolate
515 metallothionein
516 bupivacaine
517 oxygen desaturation
518 helicase
519 lectin histochemistry
520 mucinous
521 control study tobacco


http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi

 

Start A-Literature C-Literature B-list Filter Literature

AB literature

 

B-term

 

BC literature

 

lung cancer risk docetaxel tuberculosis
1: Concurrent chemoradiation therapy with docetaxel/cisplatin followed by docetaxel consolidation therapy in inoperable stage IIIA/B non-small-cell lung cancer: results of a phase I study. 2010
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2: Dose-Volume Analysis of Radiation Pneumonitis in Non-Small-Cell Lung Cancer Patients Treated with Concurrent Cisplatinum and Etoposide With or Without Consolidation Docetaxel. 2010
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3: A randomized phase II study comparing induction or consolidation chemotherapy with cisplatin-docetaxel, plus radical concurrent chemoradiotherapy with cisplatin-docetaxel, in patients with unresectable locally advanced non-small-cell lung cancer. 2010
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4: Oral Vinorelbine and Cisplatin with Concurrent Radiotherapy After Induction Chemotherapy with Cisplatin and Docetaxel for Patients with Locally Advanced Non-small Cell Lung Cancer: The GFPC 05-03 Study. 2010
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5: Non-pegylated liposomal doxorubicin and docetaxel in metastatic breast cancer: final results of a phase II trial. 2009
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6: Adjuvant gemcitabine plus docetaxel for completely resected stages I-IV high grade uterine leiomyosarcoma: Results of a prospective study. 2009
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7: Phase II study of docetaxel and carboplatin in elderly patients with advanced non-small cell lung cancer. 2009
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8: The risk of febrile neutropenia in patients with non-small-cell lung cancer treated with docetaxel: a systematic review and meta-analysis. 2009
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9: Molecular Predictors of Outcome With Gefitinib and Docetaxel in Previously Treated Non-Small-Cell Lung Cancer: Data From the Randomized Phase III INTEREST Trial. 2009
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10: A Phase I trial of weekly docetaxel and topotecan for solid tumors. 2008
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11: Predictors of toxicity of weekly docetaxel in chemotherapy-treated non-small cell lung cancers. 2008
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12: A phase II study of sequential docetaxel and gemcitabine followed by docetaxel and carboplatin as first-line therapy for non-small cell lung cancer. 2008
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13: Weekly vinorelbine versus docetaxel for metastatic breast cancer after failing anthracycline treatment. 2008
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14: Tumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients. 2008
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15: Relationship between cytochrome 3A activity, inflammatory status and the risk of docetaxel-induced febrile neutropenia: a prospective study. 2007
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16: A randomized phase II trial of two schedules of docetaxel in elderly or poor performance status patients with advanced non-small cell lung cancer. 2007
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17: A pharmacogenomic study of docetaxel and gemcitabine for the initial treatment of advanced non-small cell lung cancer. 2007
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18: A randomized phase II trial of single-agent gemcitabine, vinorelbine, or docetaxel in patients with advanced non-small cell lung cancer who have poor performance status and/or are elderly. 2007
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19: Survival without common toxicity criteria grade 3/4 toxicity for pemetrexed compared with docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC): a risk-benefit analysis. 2007
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20: Nail toxicity after treatment with docetaxel: a prospective analysis in patients with advanced non-small cell lung cancer. 2007
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21: Sequential chemotherapy with combination irinotecan and cisplatin followed by docetaxel for treatment-naive patients with advanced non-small cell lung cancer. 2007
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22: Phase I and pharmacokinetic study of docetaxel, irinotecan, and celecoxib in patients with advanced non-small cell lung cancer. 2006
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23: Randomized phase III study of 3-weekly versus weekly docetaxel in pretreated advanced non-small-cell lung cancer: a Spanish Lung Cancer Group trial. 2006
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24: A phase II study of docetaxel and carboplatin in Thai patients with advanced non-small-cell lung cancer. 2006
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25: Weekly docetaxel as second line chemotherapy for advanced non-small-cell lung cancer: meta-analysis of randomized trials. 2006
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26: Fatal interstitial pneumonitis associated with docetaxel administration in a patient with hormone-refractory prostate cancer. 2006
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27: Phase II study of carboplatin combined with biweekly docetaxel for advanced non-small cell lung cancer. 2006
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28: Phase II randomised trial comparing docetaxel given every 3 weeks with weekly schedule as second-line therapy in patients with advanced non-small-cell lung cancer (NSCLC). 2005
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29: Docetaxel and concurrent radiotherapy after two cycles of induction chemotherapy with cisplatin and vinorelbine in patients with locally advanced non-small-cell lung cancer. A phase II trial conducted by the Groupe Francais de Pneumo-Cancerologie (GFPC). 2005
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30: Docetaxel plus cisplatin is effective for patients with metastatic breast cancer resistant to previous anthracycline treatment: a phase II clinical trial. 2005
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31: Docetaxel for treatment of solid tumours: a systematic review of clinical data. 2005
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32: Docetaxel administration schedule: from fever to tears? A review of randomised studies. 2005
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33: A modified weekly docetaxel schedule as first-line chemotherapy in elderly metastatic breast cancer: a safety study. 2005
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34: Elderly subgroup analysis of a randomized phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for first-line treatment of advanced nonsmall cell lung carcinoma (TAX 326). 2005
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35: Two-dimensional radiotherapy and docetaxel in treatment of stage III non-small cell lung carcinoma: no good survival due to radiation pneumonitis. 2004
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36: Factors predicting docetaxel-related toxicity: experience at a single institution. 2004
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37: High incidence of pulmonary toxicity of weekly docetaxel and gemcitabine in patients with non-small cell lung cancer: results of a dose-finding study. 2004
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38: Phase II study of docetaxel and carboplatin as second-line treatment in NSCLC. 2004
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39: Weekly vinorelbine and docetaxel as second-line chemotherapy for pretreated non-small cell lung cancer patients: a phase I-II trial. 2004
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40: Pulmonary toxicity during prostate cancer treatment with docetaxel and thalidomide. 2003
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41: Docetaxel-based combined-modality chemoradiotherapy for locally advanced non-small cell lung cancer. 2003
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42: Vesicant-type reaction due to docetaxel extravasation. 2003
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43: Monotherapy with paclitaxel as third-line chemotherapy against anthracycline-pretreated and docetaxel-refractory metastatic breast cancer. 2002
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44: Gastrointestinal toxicity associated with weekly docetaxel treatment. 2002
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45: Nonneutropenic febrile episodes associated with docetaxel-based chemotherapy in patients with solid tumors. 2002
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46: Phase I trial of weekly docetaxel in elderly patients with non-small cell lung cancer. 2002
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47: Weekly docetaxel/paclitaxel in pretreated metastatic breast cancer. 2002
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48: Population pharmacokinetics and pharmacokinetic-pharmacodynamic relationships for docetaxel. 2001
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49: Docetaxel (Taxotere) as a single agent and in combination chemotherapy for the treatment of patients with advanced non-small cell lung cancer. 2000
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50: Docetaxel: a review of its use in non-small cell lung cancer. 2000
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51: Mesenteric venous thrombosis attributed to docetaxel. 2000
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52: Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer. 1998
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53: Docetaxel-induced subungual hemorrhage. 1997
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54: Docetaxel (Taxotere) and vinorelbine in the treatment of non-small cell lung cancer. 1997
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55: Docetaxel (Taxotere) and vinorelbine in the treatment of advanced non-small cell lung cancer: preliminary results of a phase I/II trial. 1997
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1: [A randomized study of docetaxel plus cisplatin versus paclitaxel plus cisplatin in previously untreated advanced non-small cell lung cancer.] 2008
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2: A multicenter, randomized, phase III study of docetaxel plus best supportive care versus best supportive care in chemotherapy-naive patients with metastatic or non-resectable localized non-small cell lung cancer (NSCLC). 2000
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