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研究发现吸烟饮酒均可增加食道癌风险
日本研究人员日前报告说,同时拥有吸烟、饮酒和基因类型差异等风险因子的人的食道癌发病率,是没有任何一个风险因子的人的357倍。
研究人员说,吸烟和饮酒是增加食道癌患病风险的两个生活习惯因素。研究人员分析了约1000名食道癌患者和约2700名健康人的血液。分析结果显示,如果将完全没有风险因子的人的患病危险定为1的话,那么同时拥有吸烟、饮酒和基因类型差异等因子的,其食道癌患病风险就会飙升。
研究小组介绍说,如果某人的基因属于处理酒精能力较低的类型,那么就应该更加注意控制过度吸烟和饮酒。
http://news.sina.com.cn/h/2010-12-16/093821652351.shtml
http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi
A-query: smoke or drink wine C-query: esophageal cancer |
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1 fhit
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12 beta catenin
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58 caspase-3
59 aldh2
60 mgmt
61 tcf
62 gene environment
63 xpc
64 statin
65 egfr
66 caspase
67 smad
68 cyclin
69 repair gene xrcc1
70 p16
71 bax
72 waf1
73 mmp-1
74 e2f1
75 copd
76 polymorphism promoter region
77 dna repair gene
78 leptin
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80 dickkopf-1
81 p21
82 ets
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84 serial analysis gene
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109 epidermal growth factor
110 p38
111 clock gene
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114 cytokine
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116 p16 ink4a
117 tumor suppressor
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120 caspase-9
121 phosphatidylinositol 3-kinase
122 drd2
123 bcl xl
124 exon
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126 mannose binding lectin
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163 cxcl8
164 genomic
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166 manganese superoxide dismutase
167 d1
168 fas ligand
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172 myc
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176 tnf alpha
177 ephb4
178 mnsod
179 retinoic acid receptor
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182 adiponectin receptor
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http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi
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