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Ernest A. McCulloch的论文被引用情况（2010年生理学或医学诺贝尔奖得主预测）
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加拿大安大略癌症研究所 高级科学家 Ernest A. McCulloch
获奖原因
因在 DNA 因发现干细胞和开发诱导多能干细胞而获奖
pnas.org [PDF]JE Till, EA McCulloch, L Siminovitch - Proceedings of the National …, 1964 - ncbi.nlm.nih.gov
Normal mammalian hemopoietic tissue produces a continuous supply of dif- ferentiated blood
cells whose functions are essential for life. These functional cells have limited life spans and
are incapable of self-renewal. For example, erythro- cytes lack nuclei and thus, though ...
Cited by 565 - Related articles - All 11 versions
Normal mammalian hemopoietic tissue produces a continuous supply of dif- ferentiated blood
cells whose functions are essential for life. These functional cells have limited life spans and
are incapable of self-renewal. For example, erythro- cytes lack nuclei and thus, though ...
Cited by 565 - Related articles - All 11 versions
RG Worton, EA McCulloch, JE … - Journal of Cellular …, 1969 - interscience.wiley.com
ABSTRACT Mouse bone marrow cells in suspension were separated into a number of fractions
on the basis of cell density by equilibrium density gradient centrifugation, or on the basis of cell
size by velocity sedimentation. After each type of separation, the cells from the various ...
Cited by 359 - Related articles - All 2 versions
ABSTRACT Mouse bone marrow cells in suspension were separated into a number of fractions
on the basis of cell density by equilibrium density gradient centrifugation, or on the basis of cell
size by velocity sedimentation. After each type of separation, the cells from the various ...
Cited by 359 - Related articles - All 2 versions
[CITATION] Hemopoietic stem cell differentiation.
1: Biochim Biophys Acta. 1980 Nov 26;605(4):431-59. Hemopoietic stem cell differentiation. Till
JE, McCulloch EA. Publication Types: Research Support, Non-US Gov't; Review. Mesh Terms:
Animals; Antigens, Surface/immunology; Cell Differentiation*; Cell Division; ...
Cited by 242 - Related articles - All 3 versions
… Park, DE Bergsagel, EA McCulloch - Journal of the National …, 1971 - ncbi.nlm.nih.gov
... Park CH, Bergsagel DE, McCulloch EA. PMID: 5115909 [PubMed - indexed for MEDLINE] MeSH
Terms: Animals; Cell Count; Cells*/radiation effects; Centrifugation; Culture Media; Culture
Techniques*; Hematopoietic Stem Cells/radiation effects; Injections; ...
Cited by 246 - Related articles
... Park CH, Bergsagel DE, McCulloch EA. PMID: 5115909 [PubMed - indexed for MEDLINE] MeSH
Terms: Animals; Cell Count; Cells*/radiation effects; Centrifugation; Culture Media; Culture
Techniques*; Hematopoietic Stem Cells/radiation effects; Injections; ...
Cited by 246 - Related articles
utoronto.ca [PDF]L Siminovitch, EA McCulloch, … - Journal of Cellular and …, 1963 - tspace.library.utoronto.ca
... Gurney, CW, LG Lajtha and R. Oliver 1962 A method for investigation of stem-cell kinetics.
Brit. J. Haemat., 8: 461-466. McCulloch, EA, and JE Till 1962 The sensitivity of cells from
normal mouse bone marrow to gamrna radiation in vitro and in vivo. ...
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... Gurney, CW, LG Lajtha and R. Oliver 1962 A method for investigation of stem-cell kinetics.
Brit. J. Haemat., 8: 461-466. McCulloch, EA, and JE Till 1962 The sensitivity of cells from
normal mouse bone marrow to gamrna radiation in vitro and in vivo. ...
Cited by 511 - Related articles - View as HTML - All 5 versions
hematologylibrary.org [PDF]… Becker, EA McCulloch, L Siminovitch, JE … - …, 1965 - bloodjournal.hematologylibrary.org
Page 1. The Effect of Differing Demands for Blood Cell Production on DNA Synthesis by
Hemopoietic Colony-Forming Cells of Mice By A. J. BECKER, EA MCCULLOCH, L. SIMIN0vITcH
AND J. E. TILL ... EA N'IcCUL- ... Page 3. 298 BECKER, MC CULLOCH, SIMINOVITCH AND TILL ...
Cited by 483 - Related articles - All 8 versions
Page 1. The Effect of Differing Demands for Blood Cell Production on DNA Synthesis by
Hemopoietic Colony-Forming Cells of Mice By A. J. BECKER, EA MCCULLOCH, L. SIMIN0vITcH
AND J. E. TILL ... EA N'IcCUL- ... Page 3. 298 BECKER, MC CULLOCH, SIMINOVITCH AND TILL ...
Cited by 483 - Related articles - All 8 versions
rupress.org [PDF]… , JE Till, L Siminovitch, EA McCulloch - The Journal of …, 1968 - jem.rupress.org
... BY AM WU,$ BM, JE TILL, PH.D., L. SIMINOVITCH, ProD., Am) EA McCULLOCH, MD (From the
Departments of Medicine and ... mouse hematopoietic colony- forming stem ceils can differentiate
along both erythropoietic and granulocytic lines (1). This class of stem cells is present ...
Cited by 308 - Related articles - All 11 versions
... BY AM WU,$ BM, JE TILL, PH.D., L. SIMINOVITCH, ProD., Am) EA McCULLOCH, MD (From the
Departments of Medicine and ... mouse hematopoietic colony- forming stem ceils can differentiate
along both erythropoietic and granulocytic lines (1). This class of stem cells is present ...
Cited by 308 - Related articles - All 11 versions
hematologylibrary.org [PDF]EA McCulloch - Blood, 1983 - bloodjournal.hematologylibrary.org
CELLULAR ORGANIZATION IN HEMATOPOIESIS Myelopoiesis The myeloid component of
hemopoiesis is a typical cell renewal system.' It consists of three classes of cells that differ in
their functional capacities (Fig. I). First, pluripotent stem cells are capable of self-renewal ...
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CELLULAR ORGANIZATION IN HEMATOPOIESIS Myelopoiesis The myeloid component of
hemopoiesis is a typical cell renewal system.' It consists of three classes of cells that differ in
their functional capacities (Fig. I). First, pluripotent stem cells are capable of self-renewal ...
Cited by 122 - Related articles - All 5 versions
rupress.org [PDF]RG Worton, EA McCulloch, JE Till - Journal of Experimental …, 1969 - jem.rupress.org
Two key properties of hemopoietic stem cells are their capacity for self- renewal and their capacity
for differentiation. The stem ceils in mouse hemo- poietic tissues that may be detected by their
ability to form macroscopic splenic colonies possess both these properties, but express ...
Cited by 99 - Related articles - All 8 versions
Two key properties of hemopoietic stem cells are their capacity for self- renewal and their capacity
for differentiation. The stem ceils in mouse hemo- poietic tissues that may be detected by their
ability to form macroscopic splenic colonies possess both these properties, but express ...
Cited by 99 - Related articles - All 8 versions
[CITATION] Stem cells in normal and leukemic hemopoiesis
Cited by 122 - Related articles
pnas.org [PDF]AM Wu, L Siminovitch, JE Till, EA McCulloch - Proceedings of the National …, 1968 - JSTOR
The spleen colony technique' has proved to be a useful tool for the enumera- tion of hemopoietic
stem cells in the mouse and for the study of their properties. However, since the method depends
on colony formation in the spleens of heavily irradiated' or genetically anemic2 mice, it ...
Cited by 84 - Related articles - All 8 versions
The spleen colony technique' has proved to be a useful tool for the enumera- tion of hemopoietic
stem cells in the mouse and for the study of their properties. However, since the method depends
on colony formation in the spleens of heavily irradiated' or genetically anemic2 mice, it ...
Cited by 84 - Related articles - All 8 versions
… Till, L Siminovitch, EA McCulloch - Journal of Cellular …, 1967 - interscience.wiley.com
... even with- out irradiation, support the growth of nor- mal hemopoietic colony-forming cells (Mc-
Culloch et d ... 182 A. M. WU, J. E. TILL, L. SIMINOVITCH AND EA McCULLOCH ... finding provides
cyto- logicai proof that the original marrow sus- pension contained stem cells able to ...
Cited by 224 - Related articles - All 2 versions
... even with- out irradiation, support the growth of nor- mal hemopoietic colony-forming cells (Mc-
Culloch et d ... 182 A. M. WU, J. E. TILL, L. SIMINOVITCH AND EA McCULLOCH ... finding provides
cyto- logicai proof that the original marrow sus- pension contained stem cells able to ...
Cited by 224 - Related articles - All 2 versions
hematologylibrary.org [PDF]… , C Wang, S Minkin, EA McCulloch - …, 1989 - bloodjournal.hematologylibrary.org
... Arabinoside in Culture By Jun Miyauchi. CoIm A. Kelleher, Chen Wang, Salomon Minkin, and
Ernest A. McCulloch We have proposed that the blasts in acute myeloblastic leukemia (AML)
are renewal populations maintained by a small subpopulation of stem cells. ...
Cited by 77 - Related articles - All 5 versions
... Arabinoside in Culture By Jun Miyauchi. CoIm A. Kelleher, Chen Wang, Salomon Minkin, and
Ernest A. McCulloch We have proposed that the blasts in acute myeloblastic leukemia (AML)
are renewal populations maintained by a small subpopulation of stem cells. ...
Cited by 77 - Related articles - All 5 versions
hematologylibrary.org [PDF]… Iscove, JS Senn, JE Till, EA McCulloch - Blood, 1971 - bloodjournal.hematologylibrary.org
... 1 Colony Formation by Normal and Leukemic Human Marrow Cells in Culture: Effect of
Conditioned Medium From Human Leukocytes By NN IscovE, J. S. SENN, J. E. TILL AND EA
MCCULLOCH “Conditioned medium” obtained from from the marrow of patients with acute ...
Cited by 428 - Related articles - View as HTML - All 4 versions
... 1 Colony Formation by Normal and Leukemic Human Marrow Cells in Culture: Effect of
Conditioned Medium From Human Leukocytes By NN IscovE, J. S. SENN, J. E. TILL AND EA
MCCULLOCH “Conditioned medium” obtained from from the marrow of patients with acute ...
Cited by 428 - Related articles - View as HTML - All 4 versions
hematologylibrary.org [PDF]RN Buick, MD Minden, EA McCulloch - Blood, 1979 - bloodjournal.hematologylibrary.org
... to Dr. EA McCulloch. Ontario Cancer Institute, 500 Sherbourne Street. Toronto, Ontario M4X /
K9, Canada. © 1979 by Grune & Stratton, Inc. 0006-4971/79/5402-00i2$0l.00/0 Page 2. 96 BUICK.
MINDEN, AND McCULLOCH since this property provides individual stem cells with ...
Cited by 175 - Related articles - All 4 versions
... to Dr. EA McCulloch. Ontario Cancer Institute, 500 Sherbourne Street. Toronto, Ontario M4X /
K9, Canada. © 1979 by Grune & Stratton, Inc. 0006-4971/79/5402-00i2$0l.00/0 Page 2. 96 BUICK.
MINDEN, AND McCULLOCH since this property provides individual stem cells with ...
Cited by 175 - Related articles - All 4 versions
hematologylibrary.org [PDF]WR Bruce, EA McCulloch - Blood, 1964 - bloodjournal.hematologylibrary.org
... Hemopoietic Colony-forming Cells of Mice By WR BRUCE AND EA MCCULLOCH IT IS generally
assumed (see for example, ref. ... the existence of a close relationship between colony-forming cells
and the stem cells of the erythroid series. ... 218 BRUCE AND MC CULLOCH ...
Cited by 163 - Related articles - All 4 versions
... Hemopoietic Colony-forming Cells of Mice By WR BRUCE AND EA MCCULLOCH IT IS generally
assumed (see for example, ref. ... the existence of a close relationship between colony-forming cells
and the stem cells of the erythroid series. ... 218 BRUCE AND MC CULLOCH ...
Cited by 163 - Related articles - All 4 versions
hematologylibrary.org [PDF]… , MD Minden, S Minkin, EA McCulloch - …, 1987 - bloodjournal.hematologylibrary.org
... Maintained in Short-Term Suspension Culture By Jun Miyauchi, CoIm A. Kelleher, Yu-Chung
Yang, Gordon G. Wong, Steven C. Clark, Mark D. Minden, Salomon Minkin, and Ernest A.
McCulloch The blast stem cells of acute myeloblastic leukemia (AML) ...
Cited by 139 - Related articles - All 5 versions
... Maintained in Short-Term Suspension Culture By Jun Miyauchi, CoIm A. Kelleher, Yu-Chung
Yang, Gordon G. Wong, Steven C. Clark, Mark D. Minden, Salomon Minkin, and Ernest A.
McCulloch The blast stem cells of acute myeloblastic leukemia (AML) ...
Cited by 139 - Related articles - All 5 versions
hematologylibrary.org [PDF]EA McCulloch, L Siminovitch, JE Till, ES … - …, 1965 - bloodjournal.hematologylibrary.org
... 25, 1964. EA MCCULLOCH: Associate Professor, Department of Medical Biophysics, University ...
extremely different. In a previous study (McCulloch et al.5) the spleen-colony assay for hemo-
poietic stem cells was used to investigate certain aspects of the effects of the ...
Cited by 261 - Related articles - All 6 versions
... 25, 1964. EA MCCULLOCH: Associate Professor, Department of Medical Biophysics, University ...
extremely different. In a previous study (McCulloch et al.5) the spleen-colony assay for hemo-
poietic stem cells was used to investigate certain aspects of the effects of the ...
Cited by 261 - Related articles - All 6 versions
ZB Hu, MD Minden, EA McCulloch - Leukemia, 1995 - cat.inist.fr
All-trans retinoic acid (ATRA) increases the sensitivity of AML blast cells to cytosine arabinoside
(Ara-C) or daunorubicin (DNR) when ATRA is given after drug. We have proposed that
down-regulation of bcl-2 is part of the mechanism by which ATRA regulates drug ...
Cited by 53 - Related articles - BL Direct - All 3 versions
All-trans retinoic acid (ATRA) increases the sensitivity of AML blast cells to cytosine arabinoside
(Ara-C) or daunorubicin (DNR) when ATRA is given after drug. We have proposed that
down-regulation of bcl-2 is part of the mechanism by which ATRA regulates drug ...
Cited by 53 - Related articles - BL Direct - All 3 versions
utoronto.ca [PDF]EA McCulloch, L Siminovitch, JE Till - Science, 1964 - sciencemag.org
... Our results sup- port the suggestion (18) that the "stem cells" responding to erythropoietin (19)
are not identical with the "stem cells" that give rise to spleen colonies. EA MCCULLOCH L.
SIMINOVITCH JE TILL Department of Medical Biophysics, University of Toronto, and ...
Cited by 271 - Related articles - All 6 versions
... Our results sup- port the suggestion (18) that the "stem cells" responding to erythropoietin (19)
are not identical with the "stem cells" that give rise to spleen colonies. EA MCCULLOCH L.
SIMINOVITCH JE TILL Department of Medical Biophysics, University of Toronto, and ...
Cited by 271 - Related articles - All 6 versions
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