P LINKOWSKI, J MENDLEWICZ, R … - Journal of Clinical …, 1985 - Endocrine Soc Both unipolar and bipolar depressed patients had higher 24-h mean cortisol levels (P < 0.01) than normal men, but no significant difference in 24-h mean ACTH level was found. The nadir of cortisol secretion occurred almost 3 h earlier in older normal subjects and ... Cited by 345 - Related articles - All 6 versions
[CITATION] Adoption study supporting genetic transmission in manic-depressive illness.
… , A Luxen, V De Maertelaer, P Hubain, J Mendlewicz … - Biological …, 1994 - Elsevier The authors investigated brain glucose utilization using positron emission tomography (PET) in 12 normal volunteers and 12 unipolar unmedicated depressed patients (six endogenous; six nonendogenous) following injection of [18F]fluoro-deoxyglucose (FDG). Compared by ... Cited by 164 - Related articles - All 5 versions
J Mendlewicz, S Sevy, H Brocas, P Simon, F Charon, S … - The Lancet, 1987 - Elsevier Heredity is an important factor in vulnerability to manic depression. A genetic linkage has been demonstrated between manic depression and coagulation factor IX at Xq27 with a TaqI polymorphism at the F9 locus in DNA samples from peripheral leucocytes of manic depressive probands ... Cited by 145 - Related articles - All 5 versions
… , E Lindström, J Mendlewicz, G Racagni, LS … - European …, 1998 - Elsevier The prevention of relapse in schizophrenia remains an enormous public health challenge worldwide and improvements in this area can have tremendous impact on morbidity, mortality and quality of life, as well as direct and indirect health care costs. Though there has been debate as ... Cited by 141 - Related articles - All 5 versions
J Mendlewicz, JL Fleiss, RR Fieve - Jama, 1972 - Am Med Assoc Seven families were found in which manic-depressive illness and either protan or deutan color blindness (X-linked recessive traits) occurred in successive generations. In these seven families, as well as in two others previously reported in the literature, detailed analysis ... Cited by 127 - Related articles - All 3 versions
… , E SHELLEY, J MENDLEWICZ, RR … - American Journal of …, 1973 - Am Psychiatric Assoc The authors studied 52 manic-depressive patients who were assigned to either lithium or placebo during their normal interval phases for periods up to 28 months. Patients receiving lithium had fewer manic and depres- sive episodes per patient-year than placebo patients. However, ... Cited by 120 - Related articles - All 2 versions
J MENDLEWICZ, P LINKOWSKI, M … - Journal of Clinical …, 1985 - Endocrine Soc Both unipolar and bipolar depressed patients secreted more GH than normal men (mean ± SD, 441 ± 189 µg/24 h for unipolar depressed men; 357 ± 143 µg/24 h for bipolar depressed men vs. 172 ± 101 µg/24 h for normal men (P < 0.01). This hypersecretion occurred ... Cited by 101 - Related articles - All 3 versions
J MENDLEWICZ, RR FIEVE, F … - American Journal of …, 1973 - Am Psychiatric Assoc MOUNTING EVIDEKCE for the long-term stabilizing prop- erties of lithium in bipolar manic-depressive illness is found in several controlled longitudinal studies (1-5): Al- though the time periods during which the patients were studied are not always comparable in these reports and criticisms ... Cited by 110 - Related articles - All 2 versions
… , M Monclus, D Wikler, P Damhaut, J Mendlewicz, S … - Neuroscience …, 1996 - Elsevier Serotonergic mechanisms are involved in gender-related behaviors and psychiatric conditions like aggression, eating disorders, depression, impulsivity or suicide. We studied gender differences in the living human brain type-2 serotonin receptor (5HT 2 r). Twenty-two healthy age- ... Cited by 104 - Related articles - All 4 versions
… , J Massana, J Mendlewicz, HJ MÖLLER, CB … - The Journal of clinical …, 2002 - cat.inist.fr Background: Response to antidepressant drug therapy is less than optimal for a considerable proportion of depressed patients; at present, however, few data exist to guide their rational therapeutic management. This review describes general principles for the management of such ... Cited by 106 - Related articles - BL Direct - All 3 versions
… , C Vizuete, I Morlán, J Bobes, J Mendlewicz - Journal of Psychiatric …, 1997 - Elsevier We searched for regional cerebral metabolic disturbances in patients with borderline personality disorder (BPD). Ten inpatients with BPD, no current DSM-IIIR Axis I diagnosis and free of any psychotropic substances, were compared with 15 age-matched control subjects using ... Cited by 99 - Related articles - All 4 versions
nih.gov[PDF]J Mendlewicz, JD Rainer - American Journal of Human Genetics, 1974 - ncbi.nlm.nih.gov INTRODUCTION Twin and family studies of manic-depressive (bipolar) illness strongly suggest the presence of a genetic factor in the etiology of this disease. Concordance rates for the illness in monozygotic twins are consistently greater than the rates found in dizygotic twins [1]. ... Cited by 93 - Related articles - All 3 versions
… González-Torrecillas, J Mendlewicz … - International …, 2005 - Cambridge Univ Press ABSTRACT. This study was made in an attempt todocument the effects of early treatment of poststroke depression (including fluoxetine treatment) on neuro- psychological rehabilitation (including cognitive function). Assessment mea- sures used included the Schedule for Affective ... Cited by 89 - Related articles - BL Direct - All 2 versions
… , RC Kessler, J Mendlewicz, G Racagni, AY … - …, 2000 - content.karger.com Epidemiological studies clearly indicate that posttraumatic stress disorder (PTSD) is becoming a major health concern worldwide even if still poorly recognized and not well treated. PTSD commonly co-occurs with other psychiatric disorders, and several symptoms overlap with major ... Cited by 93 - Related articles - BL Direct - All 6 versions
… , M Kerkhofs, D Bosson, J Mendlewicz, … - American Journal of …, 1993 - Am Physiological Soc Twin study of the 24-h cortisol profile: ... PAUL LINKOWSKI, ANNE VAN ONDERBERGEN, MYRIAM KERKHOFS, ... DANIELLE BOSSON, JULIEN MENDLEWICZ, AND EVE VAN CAUTER ... Sleep Laboratory, Department of Psychiatry, Erasme Hospital, Institute of Interdisciplinary ... Cited by 91 - Related articles - BL Direct - All 3 versions
J Mendlewicz, P Linkowski, J Wilmotte - The British Journal of Psychiatry, 1980 - RCP Heredity is known to be an important contributing factor in the vulnerability to manic-depressive psychosis. Family, twin and adoptionstudiescorroboratethe geneticdia thesis for the illness, but these studies do not elucidate the mode of transmission of manic depressive psychosis, ( ... Cited by 83 - Related articles - All 6 versions
J Mendlewicz, M Baron - The British Journal of Psychiatry, 1981 - RCP It has been the recent practice to discriminate between bipolar and unipolar affective disorders. Bipolar patients have a cyclical manic-depressive course of illness while unipolar patients only manifest depressions. Bipolar patients have more affective illnesses ... Cited by 72 - Related articles - All 3 versions
J Mendlewicz, JL Fleiss, M Cataldo, JD … - Archives of General …, 1975 - Am Med Assoc We interviewed available spouses and first-degree relatives of 140 bipolar and unipolar probands for current and past psychopathology, and assessed interrater reliability. Diagnoses based on direct interviews of relatives were compared with those based on reports of the probands ... Cited by 63 - Related articles - All 3 versions
J Mendlewicz, G Charles, JM Franckson - The British Journal of Psychiatry, 1982 - RCP Summary: Plasma cortisol suppression after dexamethasone administration in 113 consecutively hospitalized patients (54 patients with primary depression, 41 with secondary depression and 18 non-depressed controls) showed early morning hypersecretion of cortisol and cortisol ... Cited by 61 - Related articles - All 3 versions