Asperosaponin VI | 川续断皂苷 VI

MCE 国际站：Asperosaponin VI

中文名：川续断皂苷 VI

CAS：39524-08-8

品牌：MedChemExpress (MCE)

存储条件：-20°C, protect from light

生物活性：Asperosaponin VI，一种来自 Dispacus asper 的皂苷成分，通过 BMP-2/p38 和 ERK1/2 通路诱导成骨细胞分化^[1]。 Asperosaponin Ⅵ通过增加Bcl-2/Bax比值和降低活性caspase-3表达，以及增强p-Akt和p-CREB^[2]抑制缺氧诱导的心肌细胞凋亡。

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研究领域：Apoptosis

作用靶点：Caspase  |  Apoptosis

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

参考文献：[1]. Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6.

[2]. Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.