Tezepelumab

MCE 国际站：Tezepelumab

CAS：1572943-04-4

品牌：MedChemExpress (MCE)

存储条件：Please store the product under the recommended conditions in the Certificate of Analysis.

生物活性：Tezepelumab (AMG 157) 是一种人源化单克隆抗体 (IgG2λ)，与TSLP 特异性结合，阻止其与其异二聚体受体相互作用。Tezepelumab 可用于研究严重，不受控制的哮喘。

体外：Tezepelumab 阻断胸腺基质淋巴细胞生成素，一种上皮细胞衍生的细胞因子，与哮喘的发病机理有关[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

热销产品：Durvalumab  | Mertansine  | Futibatinib  | BT2  | Plerixafor  | Nocodazole  | SAH  | Acalabrutinib  | Picrotoxin  | Valinomycin

研究领域：Others

作用靶点：Others

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参考文献：[1]. Menzies-Gow A, et, al. Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma. N Engl J Med. 2021 May 13;384(19):1800-1809.