博文
Epcoritamab (GEN3013) 是一种双特异性 IgG1 抗体 |MedChemExpress (MCE)
|
MCE 国际站：Epcoritamab
CAS：2134641-34-0
品牌：MedChemExpress (MCE)
存储条件：Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性：Epcoritamab (GEN3013) 是一种双特异性 IgG1 抗体，可将 T 细胞重定向至 CD3×CD20+ 肿瘤细胞。
体外：Epcoritamab (30 ng/mL) 在健康供体外周血单核细胞 (PBMC) 存在的情况下诱导有效的细胞毒性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
热销产品：Tofacitinib | Dabrafenib | Stigmastanol | O-Propargyl-Puromycin | JC-1 | Conduritol B epoxide | Tocilizumab | Rituximab | Secukinumab | sulfo-SPDB-DM4
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献：[1]. van der Horst HJ, et al. Epcoritamab induces potent anti-tumor activity against malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior CD20 monoclonal antibody treatment. Blood Cancer J. 2021 Feb 18;11(2):38.
[2]. Thieblemont C, et al. Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell-Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II Trial. J Clin Oncol. 2023 Apr 20;41(12):2238-2247.
https://blog.sciencenet.cn/blog-3506747-1445296.html
上一篇：Ibuprofen ((±)-Ibuprofen) 是一种有效的、具有口服活性的选择性 COX-1 抑制剂 |MCE
下一篇：(R)-3-Hydroxybutanoic acid 是一种代谢物 |MedChemExpress (MCE)
