衣康酸是聚合物、化学品和燃料的前体，可以由许多真菌合成。衣康酸也是一种巨噬细胞特异性代谢物。衣康酸介导巨噬细胞代谢与腹膜肿瘤之间的串扰^[1][2]。https://blog.sciencenet.cn/blog-3536222-1444371.html

http://www.pubmedplus.cn/P/SearchQuickResult?wd=7167d101-1456-4d2a-8c85-cb39d83b1126

1. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.

Jonathan M Weiss,Luke C Davies,Megan Karwan,Lilia Ileva,Michelle K Ozaki,Robert Ys Cheng,Lisa A Ridnour,Christina M Annunziata,David A Wink,Daniel W McVicar

Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute (NCI) at Frederick, Frederick, Maryland, USA.

J Clin Invest (P 1558-8238 E 0021-9738) H指数：447 2018 年 128 卷 9 期 3794-3805 页

PMID：29920191 相似文献

文摘 DOI链接 PubMed CentralOvid Technologies, Inc.Europe PubMed CentralAmerican Society for Clinical Investigation

https://pubmed.ncbi.nlm.nih.gov/29920191/

J Clin Invest

. 2018 Aug 31;128(9):3794-3805.

 doi: 10.1172/JCI99169. Epub 2018 Jul 30.

Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors

Jonathan M Weiss 1, Luke C Davies 2, Megan Karwan 3, Lilia Ileva 3, Michelle K Ozaki 4, Robert Ys Cheng 1, Lisa A Ridnour 1, Christina M Annunziata 4, David A Wink 1, Daniel W McVicar 1

Affiliations expand

• PMID: 29920191

•  

• PMCID: PMC6118601

•  

• DOI: 10.1172/JCI99169

MeSH terms

• Animals

• Carboxy-Lyases

• Cell Line, Tumor

• Disease Progression

• Fatty Acids / metabolism

• Female

• Glycolysis

• Humans

• Hydro-Lyases / deficiency

• Hydro-Lyases / genetics

• Hydro-Lyases / metabolism

• Macrophages, Peritoneal / metabolism*

• Melanoma, Experimental / metabolism

• Mice

• Mice, Inbred C57BL

• Mice, Knockout

• Monocytes / metabolism

• Ovarian Neoplasms / metabolism

• Oxidative Phosphorylation

• Peritoneal Neoplasms / genetics

• Peritoneal Neoplasms / metabolism*

• Peritoneal Neoplasms / pathology

• Proteins / metabolism

• RNA, Small Interfering / genetics

• Reactive Oxygen Species / metabolism

• Succinates / metabolism*

• Tumor Burden

Substances

• Fatty Acids

• Proteins

• RNA, Small Interfering

• Reactive Oxygen Species

• Succinates

• ACOD1 protein, human

• Carboxy-Lyases

• Hydro-Lyases

• Irg1 protein, mouse

• itaconic acid

Related information

• MedGen

• PMC images

• PubChem Compound (MeSH Keyword)

LinkOut - more resources

• Full Text Sources

• American Society for Clinical Investigation

• Europe PubMed Central

• Ovid Technologies, Inc.

• PubMed Central

• Other Literature Sources

• The Lens - Patent Citations

• scite Smart Citations

• Medical

• MedlinePlus Health Information

• Molecular Biology Databases

• Guide to Pharmacology

http://www.pubmedplus.cn/P/SearchQuickResult?wd=7832d486-adb3-46c1-978f-128d619ceaad

• 主题词

• 记录数占%

01.	Animals	67 篇	87.013%
02.	Mice	60 篇	77.922%
03.	Humans	42 篇	54.545%
04.	Female	39 篇	50.649%
05.	Mice, Inbred C57BL	36 篇	46.753%
06.	Peritoneal Neoplasms	31 篇	40.260%
07.	Ovarian Neoplasms	29 篇	37.662%
08.	Cell Line, Tumor	24 篇	31.169%
09.	Macrophages, Peritoneal	23 篇	29.870%
10.	Macrophages	21 篇	27.273%

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