Bleomycin A5

MCE 国际站：Bleomycin A5

CAS：11116-32-8

品牌：MedChemExpress (MCE)

存储条件：4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

生物活性：Bleomycin A5 (Pingyangmycin) 是糖肽类抗生素，具有口服活性。Bleomycin A5 具有抗肿瘤剂、细胞凋亡诱导剂和细菌代谢物的作用。

体外：Bleomycin A5 (Pingyangmycin) 能抑制肿瘤的生长[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内：Bleomycin A5 (Pingyangmycin)（口服；18 日剂量 5 mg/kg）发生厌食、恶病质、皮肤溃疡、死亡，并观察到间质性肺炎、肾病和肾上腺皮质局灶性坏死[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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研究领域：Apoptosis

作用靶点：Apoptosis

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参考文献：[1]. Yaowu Yang, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5.

 [2]. Lin Fu-Tian, et al. Antitumor activity and preclinical pharmacological study of pingyangmycin. Zhonghua Zhongliu Zazhi. Volume: 1. Issue: 3. Pages: 161-6. Journal; English Abstract; Article. 1979.