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MCE 国际站:Sodium oleate
中文名:油酸钠
CAS:143-19-1
品牌:MedChemExpress (MCE)
存储条件:4°C, sealed storage, away from moisture
生物活性:油酸钠(Oleic acid sodium)是一种含量丰富的单不饱和脂肪酸钠[1]。 Sodium oleate 是一种 Na+/K+ ATPase 激活剂[2]。 IC50 和目标:Na+/K+ ATPase[2]
体外:油酸是人体脂肪细胞和其他组织中最常见的单不饱和脂肪酸 (FA)。油酸通过增强 AMPK 激活介导的 β-氧化促进高转移癌细胞的细胞增殖和迁移。油酸抑制胃癌 SGC7901 和乳腺癌 MCF-7 细胞系等低转移癌细胞的生长和存活[1]。
热销产品:Calycosin | TTNPB | Verapamil (hydrochloride) | Trypsin | Zanamivir | ALW-II-41-27 | L-Methionine | CL264 | Carotuximab | Propofol β-D-glucuronide
研究领域:Membrane Transporter/Ion Channel | Apoptosis
作用靶点:Na+/K+ ATPase | Apoptosis
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:[1]. Li S, et al. High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner. PLoS One. 2014 May 13;9(5):e97330.
[2]. Jack-Hays MG, et al. Activation of Na+/K(+)-ATPase by fatty acids, acylglycerols, and related amphiphiles: structure-activity relationship. Biochim Biophys Acta. 1996 Feb 21;1279(1):43-8.
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