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国际站:BT200
品牌:MedChemExpress (MCE)
存储条件:-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性:BT200 是偶联聚乙二醇的核酸适配体 BT100,可抑制 von Willebrand Factor(VWF) 与血小板糖蛋白GPIb的结合,预防动脉血栓形成。
参考文献:[1]. Zhu S, Gilbert JC, Liang Z, et al. Potent and rapid reversal of the von Willebrand factor inhibitor aptamer BT200. J Thromb Haemost. 2020;18(7):1695-1704.[2]. Zhu S, Gilbert JC, Hatala P, et al. The development and characterization of a long acting anti-thrombotic von Willebrand factor (VWF) aptamer. J Thromb Haemost. 2020;18(5):1113-1123.
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