Biotin-azide

国际站：Biotin-azide

CAS：908007-17-0

品牌：MedChemExpress (MCE)

存储条件：Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.

生物活性：Biotin-azide (N-(3-Azidopropyl)biotinamide) 是一种带有末端叠氮基的生物素。通过 Click Chemistry^[1][2]，生物素-叠氮化物可用于制备各种生物素化偶联物。

体外：使用生物素-叠氮化物探针进行点击化学功能化后交联，可以从酵母细胞中分离转录蛋白复合物[3]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献：[1]. Bruckman MA, et al. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. J Control Release. 2016;231:103‐113.[2]. Kim HY, et al. An azido-biotin reagent for use in the isolation of protein adducts of lipid-derived electrophiles by streptavidin catch and photorelease. Mol Cell Proteomics. 2009;8(9):2080‐2089.[3]. Joiner CM, et al. A Bifunctional Amino Acid Enables Both Covalent Chemical Capture and Isolation of in Vivo Protein-Protein Interactions. Chembiochem. 2017 Jan 17;18(2):181-184.