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Prof. Patrick Barth (associate Professor) at École polytechnique fédérale de Lausanne (2017 World QS Ranking, NO. 12), Switzerland is looking for a highly qualified postdoc with strong computational biophysicist, good programming skills and experience in protein modeling and simulations. He is also looking for PhD candididates. Anybody interested in, please send your CV to: patrick.barth@epfl.ch
Research areas
Enhancing structure prediction and design of soluble and membrane proteins with explicit solvent-protein interactions
Lai, J. *, Ambia, J. *, Wang, Y., Barth, P.
(Structure in press)
Reprogramming cellular functions with engineered membrane proteins.
Arber C, Young M, Barth P.
Curr Opin Biotechnol. 2017 Jul 11;47:92-101. doi: 10.1016/j.copbio.2017.06.009. [Epub ahead of print] Review.
PMID: 28709113
Computational design of ligand-binding membrane receptors with high selectivity.
Feng X, Ambia J, Chen KM, Young M, Barth P.
Nat Chem Biol. 2017 Jul;13(7):715-723. doi: 10.1038/nchembio.2371. Epub 2017 May 1.
PMID: 28459439
Toward high-resolution computational design of the structure and function of helical membrane proteins.
Barth P, Senes A.
Nat Struct Mol Biol. 2016 Jun 7;23(6):475-80. doi: 10.1038/nsmb.3231.
PMID: 27273630
A topological and conformational stability alphabet for multipass membrane proteins.
Feng X, Barth P.
Nat Chem Biol. 2016 Mar;12(3):167-73. doi: 10.1038/nchembio.2001. Epub 2016 Jan 18.
PMID: 26780406
Evolutionary-guided de novo structure prediction of self-associated transmembrane helical proteins with near-atomic accuracy.
Wang Y, Barth P.
Nat Commun. 2015 May 21;6:7196. doi: 10.1038/ncomms8196.
PMID: 25995083
High-resolution modeling of transmembrane helical protein structures from distant homologues.
Chen KY, Sun J, Salvo JS, Baker D, Barth P.
PLoS Comput Biol. 2014 May 22;10(5):e1003636. doi: 10.1371/journal.pcbi.1003636. eCollection 2014 May.
PMID: 24854015
Naturally evolved G protein-coupled receptors adopt metastable conformations.
Chen KY, Zhou F, Fryszczyn BG, Barth P.
Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13284-9. doi: 10.1073/pnas.1205512109. Epub 2012 Jul 30.
PMID: 22847407
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